Publications by authors named "Miriam J Pougin"
Article Synopsis
- Mesoporous metal-organic frameworks (MOFs) are promising for drug delivery, but their stability in water limits their use, with some exceptions like the PCN-series, which have shown durability in various pH levels.
- This study investigates the stability of PCN-333 nanoparticles (nPCN) in different solvents and reveals that nPCN actually deteriorates in water, losing its octahedral shape and porosity within just 2 hours.
- Through molecular dynamics simulations, the research uncovers that the breakdown of PCN-333 in water is caused by hydrolysis, where water molecules disrupt the metal-ligand bonds that hold the structure together.
Pore topology and chemistry play crucial roles in the adsorption characteristics of metal-organic frameworks (MOFs). To deepen our understanding of the interactions between MOFs and CO during this process, we systematically investigate the adsorption properties of a group of pyrene-based MOFs. These MOFs feature Zn(II) as the metal ion and employ a pyrene-based ligand, specifically 1,3,6,8-tetrakis(-benzoic acid)pyrene (TBAPy).
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