Introduction: Primary Hyperoxaluria type I (PH1) is a rare autosomal recessive disease caused by lack or dysfunction of the liver peroxisomal enzyme alanine: glyoxylate aminotransferase, AGT.
Aims: To conduct clinical and genetic characterization of Druze and Muslim Arab patients with PH1 in Northern Israel.
Methods: In the last 20 years, 36 children and families were diagnosed and treated in the Nephrology-Genetic Clinic at the Galilee Medical Center.