Publications by authors named "Miriam Fernandez-Pacheco"

Article Synopsis
  • The study investigates the impact of the time to initiate neoadjuvant chemotherapy (TTNC) on survival rates in patients with early-stage triple negative breast cancer (TNBC).
  • A cohort of 270 patients was analyzed, revealing that those who began chemotherapy within 0-42 days post-diagnosis had significantly better 5-year overall survival rates compared to those starting later.
  • The findings suggest that delaying treatment beyond 42 days may reduce survival, highlighting the importance of timely intervention in certified breast care centers.
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Purpose: As breast-conserving surgery (BCS) has become the standard for treatment of early breast cancer, the need for new technologies to improve intraoperative margin assessment has become clear. Close or positive margins during BCS lead to additional surgeries, treatment delay, additional stress for patients and increasing healthcare cost. Automated three-dimensional breast ultrasound (ABUS) systems are meant to overcome the shortcomings of hand-held ultrasound (HHUS).

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Background: Several international studies reported relatively high re-excision rates due to residual tumor in breast conserving surgery (BCS). Cavity shaving (CS) is a surgical strategy to reduce re-excision rates. This study aimed to investigate the effect of circumferential cavity shaving during BCS to reduce residual tumor.

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