Publications by authors named "Miren Z Zubero-Sulibarria"

Circulating recombinant forms (CRFs) are important components of the HIV-1 pandemic. Among 110 reported in the literature, 17 are BF1 intersubtype recombinant, most of which are of South American origin. Among these, all 5 identified in the Southern Cone and neighboring countries, except Brazil, derive from a common recombinant ancestor related to CRF12_BF, which circulates widely in Argentina, as deduced from coincident breakpoints and clustering in phylogenetic trees.

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Article Synopsis
  • Circulating recombinant forms (CRFs) play a significant role in the HIV-1 pandemic, with 16 identified BF intersubtype recombinants primarily from South America, notably CRF12_BF.
  • A new BF recombinant cluster found in Bolivia is now recognized as a part of a larger cluster of 39 viruses from multiple countries, especially Spain, Bolivia, and Peru, demonstrating diverse origins and connections.
  • Genetic analyses identified a new CRF, named CRF89_BF, which likely emerged in Bolivia around 1986 and is the fifth member related to CRF12_BF, underscoring the complex nature of HIV-1 evolution in the region.
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