Publications by authors named "Mirella Scipione"
Article Synopsis
- Sensor-augmented continuous subcutaneous insulin infusion (CSII) therapy shows better glucose control compared to sensor-augmented multiple daily injections (MDI) therapy in children, as evidenced by lower mean glucose levels and different variability indexes.
- A study involving 55 children revealed that those on CSII made more insulin boluses and had higher glucose management quality, while the MDI group had more instances of high blood glucose levels.
- Although both groups experienced similar rates of mild hypoglycemia, the findings indicate CSII therapy is generally more effective for managing blood sugar in daily life, despite potential inaccuracies in low glucose measurements from sensors.
The association between maturity onset diabetes of the young (MODY) and type 1 diabetes mellitus (T1DM) has been rarely described. We report two patients affected by MODY who developed T1DM. Case 1: a 4-yr-old girl referred for glycosuria presented hemoglobin A1c (HbA1c) of 6.
View Article and Find Full Text PDFObjective: To evaluate the frequency of normalization, the persistence of remission, and the impact on normalization of glycemic control and lipid profile, we analyzed data from a retrospective observational cohort study of type 1 diabetic children and adolescents with abnormal urinary albumin excretion (UAE).
Research Design And Methods: All diabetic children and adolescents (n = 41) who had persistent abnormal UAE in the period of 1984 to 2008 and followed up until 2009 (follow-up duration = 13.1 ± 6.
Objective: We describe a maturity-onset diabetes of the young (MODY) case with mutations involving both HNF4A and HNF1A genes.
Research Design And Methods: A male patient was diagnosed with diabetes at age 17; the metabolic control rapidly worsened to insulin requirement. At that time no relatives were known to be affected by diabetes, which was diagnosed years later in both the parents (father at age 50 years, mother at age 54 years) and the sister (at age 32 years, during pregnancy).