Publications by authors named "Mireia Vargas"

Introduction: We aimed to identify the incidence and risk factors of spontaneous preterm birth in pessary carriers with singleton pregnancies and a short cervix in the mid-trimester of pregnancy.

Material And Methods: Patient data were obtained from the PECEP Trial. We analyzed singleton pregnancies in pessary carriers with a short cervix (≤25 mm) between 18 and 22 gestational weeks.

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Article Synopsis
  • Proinflammatory factors like interleukin-6 (IL-6) are crucial in understanding preterm labor and chorioamnionitis, prompting this study to establish normal IL-6 reference levels in amniotic fluid.
  • The research involved 98 asymptomatic pregnant women who underwent amniocentesis, measuring IL-6 using advanced fluorescence immunoassay techniques, with findings indicating no reported cases of chorioamnionitis.
  • Results showed that IL-6 levels have a normal distribution and are unaffected by various factors like gestational age, maternal age, or lifestyle habits, providing a baseline reference for future studies.
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Background: Cervical pessary placement as an intervention for preterm birth prevention in women with a short cervix is a simple, painless procedure with few complications and a reasonable cost. Its efficacy depends on the expertise of the obstetrician performing the procedure. Therefore, it is reasonable to assume that untrained obstetricians with no expertise in pessary placement are more likely to insert the pessary incorrectly, thereby reducing its efficacy.

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  • The study aimed to compare the vaginal microbiome of low-risk and high-risk pregnant women to see if it relates to preterm birth.
  • Pregnant women were divided into three groups: control (normal cervix), pessary, and cerclage, and their vaginal microbiomes were analyzed at two different stages during their pregnancy.
  • Results showed that women with a short cervix had a different microbiome composition and a significant increase in microbial diversity after cerclage intervention, while such changes were not observed in the pessary or control groups, along with an increased risk of preterm labor in the cerclage group.
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Objective: To demonstrate the step-by-step surgical technique of robotic-assisted transabdominal cerclage, highlighting a new posterior compartment approach.

Design: Stepwise explanation of a surgical technique using surgical video.

Setting: The procedure was performed at the Obstetrics and Gynecology Department, Hospital Vall d'Hebron in Barcelona, Spain, a tertiary medical center.

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Objectives: To identify ultrasound-assessed cervical characteristics, modified after pessary placement, which could be predictive of spontaneous preterm birth (sPTB) at < 34 weeks of gestation (WG) or severe adverse perinatal outcomes (APO).

Study Design: This prospective observational study conducted at Vall d'Hebron Universitary Hospital assessed multiple cervical characteristics in women with short cervical length (CL). All participants were examined by transvaginal ultrasound before and immediately after a cervical pessary was placed.

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