Publications by authors named "Mirei Kohno"
Article Synopsis
- - This study investigates the role of C-terminal protein expression in detecting genetic fusions associated with non-small cell lung cancers, focusing on the oncogenes ALK, RET, and ROS1.
- - Researchers analyzed mRNA and protein levels in 37 lung cancer cell lines and tissue specimens, finding significant increases in C-terminal expression for fusion-positive samples, particularly in ALK and ROS1.
- - Results suggest that measuring C-terminal protein levels could effectively indicate ALK or ROS1 fusions, but for RET fusion detection, additional methods are necessary due to its inconsistent expression patterns.
