Publications by authors named "Mircea V Nanulescu"

Background: Induced sputum in children with bronchial asthma represents a non-invasive method of bronchial inflammation assessment. The main objective of our study was to analyze the cellularity of sputum in patients with bronchial asthma according to the level of disease control and the controlling therapy (with/without inhaled glucocorticoids). The second objective was to establish the correlation between sputum cellularity and other indirect parameters used to evidence bronchial inflammation (exhaled nitric oxide) and obstruction (forced expiratory volume in 1 second).

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Background: Exhaled nitric oxide (eNO) assessment in children with bronchial asthma (BA) is an easy and non-invasive test that provides informations on the presence of bronchial inflammation.

Methods: The study included 110 children aged between 5-18 years with a diagnosis of BA. The patients were assessed clinically (objective examination, questionnaire regarding the disease control) and by medical tests (exhaled breath analysis for nitric oxide, induced sputum, spirometry).

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Unlabelled: The AIM of the study was to validate some of the imaging criteria for voiding dysfunction in children.

Material And Methods: The study included a number of 55 children with voiding dysfunction symptoms. They were investigated clinically as well as through imaging techniques: renourinary ultrasound, voiding cystourethrography and cystometry.

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Background: The prevalence of asthma and allergy has increased during recent decades.

Objective: We investigate the prevalence of asthma and other allergic diseases in children aged 13-14 years and we evaluate the trend of prevalence after an interval of 6 years.

Material And Methods: We used a core questionnaire designed by the International Study of Asthma and Allergy in Children.

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The authors present the case of a male patient of 9 years of age admitted for thoracic pain. The clinical evaluation and the imaging exams (chest X-ray, ultrasonography exam of the chest and thoracic computer tomography) reveal a tumor of the thoracic wall. The child was referred to the surgery.

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The quality of life is a subjective parameter that evaluates the impact of asthma on daily life of the child. The authors evaluated the evolution of the quality of life score in children with persistent asthma and analyzed the impact of association of allergic rhinitis on this parameter. The evaluation of the quality of life was based on a questionnaire with 23 items (PAQLQ), which was applied on 54 children with asthma (35 of them having rhinitis allergic associated to asthma).

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