Publications by authors named "Mircea Stefan Marinescu"
Article Synopsis
- HEV (hepatitis E virus) infects people and can trigger a response from special immune cells called CD4 T cells, which help fight the virus and make antibodies.
- Researchers studied these CD4 T cells and antibodies to better understand their roles in people with HEV infections.
- They found that the main target for these immune cells is a part of the virus called the capsid, and while antibodies against the virus are strong at first, they decrease over time.
SARS-CoV-2 spike mRNA vaccines mediate protection from severe disease as early as ten days after prime vaccination, when neutralizing antibodies are hardly detectable. Vaccine-induced CD8 T cells may therefore be the main mediators of protection at this early stage. The details of their induction, comparison to natural infection, and association with other arms of vaccine-induced immunity remain, however, incompletely understood.
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