Publications by authors named "Mircea Istodorescu"
Article Synopsis
- Tissue engineering aims to regenerate new tissue, but progress has been limited, making the choice of biomaterial for scaffolding crucial.
- The study focuses on creating hydrogels from biocompatible natural polymers, specifically gelatin and a pectin derivative, to enhance bone regeneration.
- A double-reinforcement approach using Si-based compounds and cellulose nanofibers, along with a dual cross-linking method, is proposed to improve flexibility and strength in scaffolding materials.
Nano-apatite and gelatin-alginate hydrogel microparticles have been prepared by a one-step synthesis combined with electrostatic bead generation, for the reconstruction of bone defects. Based on the analysis of bone composition, architecture and embryonic intramembranous ossification, a bio-inspired fabrication has been developed. Accordingly, the mineral phase has been in situ synthesized, calcifying the hydrogel matrix while the latter was crosslinked, finally generating microparticles that can assemble into a bone defect to ensure interconnected pores.
View Article and Find Full Text PDF