Publications by authors named "Mircea Balasanian"
: Drug-related bradyarrhythmia is a well-documented major adverse event among beta-blocker users and a potential cause for hospitalization or additional interventions. Whether beta-blocker use is associated with specific bradyarrhythmia presentations, and how this relates to other predisposing factors, is not well known. We aim to evaluate the association between beta-blocker use and the type of atrioventricular (AV) conduction disorder in patients with symptomatic bradycardia.
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- The study compares the prognosis of local thrombolysis versus systemic thrombolysis in patients with high-risk pulmonary embolism over 13 years, involving 37 patients treated locally and 36 systemically.
- Local thrombolysis led to a complete remission of cardiogenic shock and a significantly lower in-hospital mortality rate compared to systemic thrombolysis.
- Both treatment methods had similar outcomes regarding pressure gradient reduction and long-term survival rates, but local thrombolysis showed better improvement in residual pulmonary hypertension during the 24-month follow-up.
Critical lesion of the unprotected left main coronary disease carries a tremendous mortality burden, often associated with a diabetes status or multivessel disease, with coronary artery bypass grafting being the standard treatment for over 40 years. Percutaneous coronary intervention with drug eluting stents should be taken into consideration and could be a better option for patients with low SYNTAX score as validated by the recently published studies. This review summarizes the major randomized clinical trials and meta-analyses concerning the debate regarding percutaneous coronary intervention with drug eluting stents versus coronary artery bypass grafting for unprotected left main coronary disease, along with the latest European and American revascularization guidelines and tries to shed light on this matter.
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