In the field of small animal studies, the array coil imaging has become increasingly important. In this paper, a dedicated two-channel array coil operating at 300 MHz (7 T) for high-resolution MRI (HR-MRI) of the rat knee cartilage is presented. The average gain in signal-to-noise ratio (SNR) compared to a 15-mm multipurpose surface coil was 2.
View Article and Find Full Text PDFZebrafish embryo is a well-established model used in many fields of modern experimental biology. We demonstrate that it provides a promising model platform for exploring fundamental MR aspects that can be used to screen and study active MR molecules before progressing to more complex living systems. Setting up a dedicated MRI methodology, we arrayed a large number of living embryos, which were microinjected at very early stages of development with different contrast agents.
View Article and Find Full Text PDFPurpose: This study assessed the value of high-resolution magnetic resonance imaging (MRI) of the distal colon by means of a dedicated endoluminal magnetic resonance receiver coil on a 1.5-T clinical scanner.
Materials And Methods: To this end, single-loop, receive-only radio-frequency coils, housed in 18 F sheaths, were built.
With the development of interventional MRI, heating of biological tissues along the metallic wires in the MRI scanner has become an important issue. To assess thermal response to RF exposure during MRI, we studied the temperature elevation near nonmagnetic metallic wires. All tests were performed on a 1.
View Article and Find Full Text PDFRationale And Objectives: Despite improvements, spatial resolution and image quality with routine surface coils are too limited when detailed information about the gastrointestinal layers is requested. The objective of our feasibility study was to evaluate the potential of a dedicated endoluminal coil to depict different layers of the colonic wall in an in vitro small animal model.
Materials And Methods: A single-loop coil (40 mm length, 5 mm width) was built using IC (printed circuit) technology.
The extraction of the Nuclear Magnetic Resonance (NMR) spectra of samples having smaller and smaller volumes is a real challenge. Either these reductions of volume are dictated by the difficulties of production of sufficiently large samples or by necessities of miniaturisation of the analysing system, in both cases a careful design of the radiofrequency coil, ensuring an optimum reception of the NMR signal, is required. We have also evaluated the usefulness of electromagnetic simulation software for the design and optimisation of these radio-frequency coils, which are more and more used in biology and health research projects.
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