[Allergic asthma and interleukins 2, 4, 5, 6 and 12 and gamma interferon levels].

Background: Asthma is an inflammatory chronic illness, in which mastocyt cells, basophils, T lymphocytes, eosinophils and cytokines play a role. Its association with the production of TH2 cytokines is not well known, but it is considered an aberrant immune response, yielding the activation and recruitment of a number of effector cells (mastocyts/eosinophils) and the appearance of clinical symptoms.

Objective: To determine the serum values of the interleukins 2, 4, 5, 6 and 12 and gamma interferon in relation to the severity degree of asthma and the time of immunotherapy in patients with stable chronic allergic bronchial asthma.

[Presence of anti-Helicobacter pylori, antithyroid, and high-affinity IgE receptor antibodies in patients with chronic urticaria].

Background: Chronic urticaria is characterized by erythematous wheals during more than 6 weeks. In 47% of the patients it is associated to Helicobacter pylori infection; in 50%, to antibodies (Abs) against the high affinity receptor of the IgE, and in 12 to 20% to antithyroid's antibodies (antithyroglobuline, mychrosomals) and, from these, 25% have alterations of the thyroid function.

Objective: To determine the presence of the anti-Helicobacter pylori and anttihyroids antibodies and the high affinity anti-receptor of the IgE in healthy subjects and patients with chronic urticaria.

[Quality of life evaluation in the patient with allergic rhinits].

Background: The introduction of the evaluation tools, such as the quality of life-questionnaires, allows to assess how functional alterations due to an illness affect the patient's life.

Objective: To know the emotional, social and occupational state of allergic rhinitis patients.

Material And Methods: Quality of life questionnaires were applied once to a group of 50 patients with allergic rhinitis diagnosis from the clinic immunology and allergy service, from May to August 2002.

[Failure of allergen-based immunotherapy in adults with allergic asthma].

Background: The allergic asthma is the reversible chronic inflammatory process at the airways, secondary to exaggerate reply to the allergens exposition, its treatment includes: avoiding the exposure to allergens, pharmacology therapy and the specific immunotherapy with allergens (ITA), which is based on the growing dosages of the extract allergenic; the objectives are to modify the immune response and to improve the allergic disease. The ITA can fail due to causes attributable to the patient, vaccine-inherent causes and/or factors related to the allergic disease.

Objective: To determine the main causes of specific immunotherapy with allergens' failure in our hospital.

[Preeclampsia-eclampsia: a change in utero-placental microcirculation. Immunologic, histologic, and biochemical features].

Background: To know the alterations in the microcirculation of the placenta, umbilical cord, as well as the immune and hemorrheologic disorders in preeclampsia-eclampsia.

Material And Methods: Two groups were conformed, 30 patients each, all of them with pregnancy of more than 24-week gestation. Group A included patients with preeclampsia-eclampsia and group B (control group) included women with normal pregnancy.

[Hyper-IgM syndrome: mucocutaneous lesions and neutropenia].

The hyper-IgM syndrome is a rare immunodeficiency disease in which the ability of B cells to switch immunoglobulin production from IgM to IgG, IgA and IgE is defective. The deficiency of IgG and IgA leads to recurrent infections of the respiratory tract, but some patients are susceptible to infection with opportunistic microorganisms, such as Cryptococcus neoformans, and also are prone to neutropenia and mucocutaneous ulcerations. We report a case of a two-year-old boy that was given the diagnosis of the hyper-IgM syndrome on the basis of low serum concentrations of IgG and IgA and high serum levels of IgM associated with C.

[use of a Staphylococcus bacterial vaccine in pediatric patients with chronic sinusitis].

Introduction: The antigenic extracts of bacterial vaccine (Staphylococcus aureus) they increase the phagocitosis, the immunoglobulins concentrations and they help in the immunologic response.

Objective: To determine the effectiveness of the bacterial vaccine in patient pediatric with chronic sinusitis.

Material And Method: Through a prospective, observational, descriptive and logitudinal study 50 patients were studied with clinical and radiological diagnosis of chronic sinusitis in the period of May from 1997 to July of 1998; they talked to three outlines of antibiotics, they were made studies of cytology hematic, of snot, perspired pharyngeal and immunoglobulin determination and x-rays of breasts paranasals.

[Vasculitis and viral infection].

Viruses have been implicated in vasculitis. To determine activity of viral infection associated with vasculitis. 17 patients with vasculitis had been in immunological and antiviral antibodies evaluation.

[Skin test with aeroallergens untested in Mexico].

This study was carried out to prove that some molds even not studied in Mexico can be able to incit a positive skin test. We tested 43 adults (15-45 years old), 34 of them suffering respiratory allergy verified by roentgenography and laboratory tests including traditional intradermic allergic test. 9 subjects served as control group.

[Multiple sclerosis].

Multiple sclerosis, a neurological problem in which mechanisms of autoimmunity and immunodeficiency may cause damage appears with a variable range of immune response. In this paper we classify in three grate subgroups the alterations observed in our patients: Type I: specific defect of immune response; Type II: immunodeficiency with autoimmune responses; Type III: mixed responses: autoimmunity with specific defect of immune response and increased cytotoxicity. A rational explanation about the various immunological changes emerged from comprehension of these mechanisms of response and following these hypothesis we propose an immunological classification of multiple sclerosis in other to reach more effective therapeutic goals.

[Skin hypersensitivity: intradermal hypersensitivity to allergen extracts and its relation to the place of residence].

A retrospective review of 308 clinical files of patient to respond at immunological and clinical allergic service of the Centro Medico 20 de Noviembre, ISSSTE for suffer with allergica illnes, realized by aeroalergens sensitization and determination frequency (intradermoreactions mediated) and relation to area living. The patients was highly sensitive at dust and dermatophagoides (75 and 40% respectively) others aeroalergen caused sensitization in the Capriola dactylon (37%), Amarantus palmieri (35.5%), Fracxinus (34.

[Effectiveness of sodium cromoglycate in the reduction of bronchodilator doses in asthmatic patients].

Thirty asthmatic patients, ages ranging from 6 to 72 years, who were submitted to a 14 weeks clinical evaluation, were studied measuring the severity of dysnea, coughing, expectoration and wheezing. Sodium chromoglycate (SCG) was administered in aerosol starting the second week of the study and the doses of bronchial dilators was reduced starting the fourth week, with a 25% decrease in the total established initial dosage, every two weeks. In this study, SCG showed to be useful in decreasing symptoms caused by bronchial hyperreactivity and the use of bronchial dilators in 70% of asthmatics who react with the presence of just one risk factor (cold, the most frequent).

[Intestinal lymphagiectasis. Use of immunoregulators].

The authors present a patient with intestinal lymphangiectasis discussing the pathophysiology, diagnosis and immunologic treatment instituted which was with mebendazole, sulfazalosopyridine and oral calcium. Immunoglobulins and T and B leukocytes showed increase together with clinical improvement in the diarrheal picture.

[Electron microscopy of the intestinal mucosa in a case of lymphangiectasis].

The morphology of the intestinal mucosa was reviewed using light microscopy and transmission electron microscopy from a two year-old male patient with protein losing primary intestinal lyphangiectasis. Diagnostic studies ruled out recognized forms of secondary intestinal lymphangiectasia (e.g cardiac, hepatic, renal diseases or lymphoreticular cancer).

[Immunological status of patients with amebic hepatic abscess].

The authors studied 10 cases of amoebic hepatic abscess documented by clinical evidence and confirmed by laboratory tests, liver scan and a good response to treatment. The immunological state of the patients was determined by protein electrophoresis, immunoelectrophoresis, counter-immunoelectrophoresis, radial immunodiffusion and roset formation for T and B lymphocytes. It is concluded that the alterations of cellular and humoral immunity is evident in cases of amoebic hepatic abscess; this alterations are more clear in the acute form of the illness and the immunological deficiency is more significant in the celular immunity.