Computer aided analysis of breast MRI enhancement kinetics using mean shift clustering and multifeature iterative region of interest selection.

Purpose: To evaluate automatic characterization of a breast MR lesion by its spatially coherent region of interest (ROI).

Materials And Methods: The method delineated 247 enhancing lesions using Otsu thresholding after manually placing a sphere. Mean Shift Clustering subdivided each volume, based on features including pharmacokinetic parameters.