Publications by authors named "Miranda L Allbee"
(1) Background: Renal immune cells and lymphatic vessel (LV) density have been reported previously to be increased in multiple mouse models of hypertension (HTN). However, whether interstitial levels of HTN stimuli such as angiotensin II, salt, or asymmetric dimethylarginine have a direct or indirect effect on lymphangiogenesis is unknown. We hypothesized that these 3 HTN stimuli directly increase lymphatic endothelial cell (LEC) proliferation, LEC 3-D matrix invasion and vessel formation, and sprouting of mouse mesometrial LVs.
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- Time restricted feeding (TRF) may help lower blood pressure and reduce inflammation in kidneys, linked to hypertension.
- In studies with mice, TRF led to a significant decrease in blood pressure and reductions in immune cell accumulation in the kidneys without affecting food intake or body weight.
- The results indicate that TRF could improve kidney function in hypertensive conditions by targeting innate immune cells.