Brain mechanisms of rumination and negative self-referential processing in adolescent depression.

Background: Depression is linked to cognitive biases towards more negative and less positive self-relevant information. Rumination, perseverative negative thinking about the past and the self, may contribute to these biases.

Methods: 159 adolescents (12-18 years), with a range of depression symptoms, completed the SRET during fMRI.

Factors Influencing Show Rates of Emergency Department Referrals to Primary Care Safety Net Clinics.

Background: Utilization of emergency departments for non-urgent conditions has been a longstanding problem leading to excessive health care spending, unnecessary testing, and missed opportunities for patients to form longitudinal relationships with primary care clinicians. The Milwaukee Health Care Partnership established the Emergency Department Care Coordination program to decrease avoidable emergency department visits and connect high-risk individuals with primary care medical homes. Emergency department providers from 8 hospitals schedule patients to safety net clinics to establish follow-up care.

SARS-CoV-2-Associated Guillain-Barre Syndrome Obscured by Diabetes Mellitus Peripheral Neuropathy.

Multiple neurological complications, including Guillain-Barre syndrome (GBS), have been reported in association with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak. GBS has well-known associations with viruses such as influenza, human immunodeficiency virus, Zika, severe acute respiratory syndrome, Middle East respiratory syndrome, Epstein-Barr virus, and cytomegalovirus. Till date, there have been around 50 distinct published cases of GBS occurring concurrently or shortly after SARS-CoV-2 infection.

Who was he? Reflections on China's first medical 'naturalist'.

This paper examines the reasons why Physician He (Yi-He, sixth century BCE) was regarded as a founder in the classical medical tradition of China. By most accounts, Physician He's importance owes much to his theoretical innovations. In contrast to earlier healers, Physician He purportedly framed the aetiology of illnesses solely in terms of natural causes, as opposed to attributing sickness to gods or demons.

Cryptosporidium source tracking in the Potomac River watershed.

To better characterize Cryptosporidium in the Potomac River watershed, a PCR-based genotyping tool was used to analyze 64 base flow and 28 storm flow samples from five sites in the watershed. These sites included two water treatment plant intakes, as well as three upstream sites, each associated with a different type of land use. The uses, including urban wastewater, agricultural (cattle) wastewater, and wildlife, posed different risks in terms of the potential contribution of Cryptosporidium oocysts to the source water.