Evaluation of the serum β2 Microglobulin level in patients with systemic lupus erythematosus and its correlation with disease activity.

Background: Designation of disease activity is serious for the management of systemic lupus erythematosus (SLE). Serum level of β2 microglobulin (β2M) may be associated with illness activity in SLE disease. Since the role of β2M for assessing of illness activity in SLE is not completely clear, the current study aimed to discern evaluation of β2M in patients with SLE and its correlation with sickness activity.

Postsplenectomy Kawasaki disease in a 17-year-old male.

Kawasaki disease (KD) is characterized with an acute systemic vasculitis of the medium- and small-sized vessels. This disease mainly involves children within the age of 6 months to 5 years and it is often self-limited and patients seem to recover well; however, it may lead to devastating and fatal cardiovascular complications such as coronary artery aneurysm. Thus, early diagnosis and appropriate management of this disease have a significant effect on improving the prognosis and preventing its serious complications.

Evaluation of serum uric acid level in systemic lupus erythematosus patients with normal and high pulmonary arterial hypertension.

Background: Systemic lupus erythematosus (SLE) is a life-threatening multisystem inflammatory condition affected any organ system. Considering the role of uric acid as a pro-inflammatory compound in high pulmonary arterial pressure, serum levels of uric acid and its relation to severity and duration of the disease were assessed in SLE patients.

Methods: As a cross-sectional study, 75 patients with SLE were enrolled in Imam Khomeini Hospital and Sahand Clinic.

Very Rare Presentation of Cerebrovascular Accident in 20-Year-Old Man With Familial Mediterranean Fever-Case Report.

Familial Mediterranean fever (FMF) is characterized by recurrent episodes of fever accompanied by serosal, synovial, or cutaneous inflammation. The central nervous system (CNS) is rarely involved in FMF. The CNS involvement includes demyelinating lesions, posterior reversible encephalopathy syndrome, pseudotumor cerebri, optic neuritis, and cerebral vasculitis.

Serum levels of IL-18 in Iranian females with systemic lupus erythematosus.

Unlabelled: IL-18 is a member of the IL-1 family of cytokines but due to its unique inflammatory and imimunoregulatory properties it is suggested that it plays important roles in autoimmune and inflammatory diseases like as systemic lupus erythematosus (SLE).

Methods: The current study was sought to evaluate serum levels of IL-18 in Iranian females with SLE. Serum samples of 25 patients with low disease activity, SLE-DAI score < 7, 25 with high disease activity, SLE-DAI score > or = 7 and 25 normal subjects were assessed for IL-18, anti-ds-DNA, C3, C4 and other lab findings using appropriate methods.

Diagnostic performances of high resolution trans-thoracic lung ultrasonography in pulmonary alveoli-interstitial involvement of rheumatoid lung disease.

Introduction: Alveolointerstitial involvement is a common manifestation in patients with connective tissue disorders. The aim of our study is to investigate the utility of modified TTUS scoring system compared with HRCT findings of pulmonary involvement in rheumatoid lung disease.

Material And Methods: Thirty one consecutive patients with a suspected diagnosis of rheumatoid lung involvement were examined with high resolution transthoracic ultrasonography for detecting of ultrasonographic comet tail signe as a ultrasonographic marker of lung involvement in alveolointerstitial involvement in rheumatoid lung disease and the results of them were compared with High resolution computed tomography as gold standard method for diagnosis of lung involvement in this patients.

Evaluation of disease activity in ankylosing spondylitis; diagnostic value of color Doppler ultrasonography.

Introduction: Spondyloarthropathies including ankylosing spondylitis (AS) require early diagnosis to prevent irreversible changes. Sacroiliitis is a common initial manifestation of AS and is frequently diagnosed by magnetic resonance imaging (MRI). The goal of our study was to assess color Doppler ultrasonography as a potential diagnostic tool in suspected sacroiliitis in comparison with MRI representing the gold standard.