Publications by authors named "Miralba Freire de Carvalho Ribeiro da Silva"
Performance Assessment of Treponemal and Nontreponemal Tests for the Diagnosis of Acquired Syphilis.
Am J Trop Med Hyg
June 2024
There are a variety of nontreponemal test (NTT) and treponemal test (TT) kits for the serologic diagnosis of syphilis. Because of the complexity of the infection (multiple clinical stages) and the different antigens used in these kits, a systematic evaluation of the accuracy of the currently available commercial tests is warranted. Our objective was to evaluate the performance of commercially available tests for the diagnosis of syphilis infection.
View Article and Find Full Text PDFEvaluating the diagnostic accuracy of TpN17 and TmpA recombinant proteins in syphilis detection: a phase II study.
Front Microbiol
February 2024
Syphilis is a sexually transmitted infection (STI) caused by the spiral bacterium . Diagnosis is based on epidemiology, clinical and serology, but serodiagnosis is challenging because distinct clinical forms of the infection may influence serological performance. Several recombinant -proteins have already been tested for syphilis diagnosis and they are critical to achieve high accuracy in serological testing.
View Article and Find Full Text PDFAetiological molecular identification of sexually transmitted infections that cause urethral discharge syndrome and genital ulcer disease in Brazilian men: a nationwide study.
Sex Transm Infect
April 2024
Article Synopsis
- Limited knowledge of urethral discharge syndrome (UDS) and genital ulcer disease (GUD) in Brazil prompted a nationwide study aimed at updating treatment guidelines from 2018 to 2020.
- The study involved collecting samples from male participants across Brazil and utilized advanced PCR testing to identify various pathogens linked to UDS and GUD.
- Findings revealed that Neisseria gonorrhoeae was the most common pathogen in UDS, while herpes simplex virus type 2 was most prevalent in GUD, highlighting significant coinfection rates and providing crucial insights into the local aetiology of these conditions.