Publications by authors named "Mir-Hossein Seyed-Mohammadzad"

Background: Cardiac syndrome X (CSX) has been associated with endothelial dysfunction and inflammation. We conducted a case-control study to evaluate the association between plateletý and endothelial-derived microparticles (PMPs and EMPs), as specific quantitative plasma markers of endothelial dysfunction, and the presence of CSX.

Methods: The present study was conducted on 40 CSX patients and 19 healthy individuals.

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Objective: Evidence indicates that probiotic supplements may improve or prevent depression. Little is known about the effects of probiotic supplementation on symptoms of depression and quality of life (QOL) in patients with myocardial infarction (MI).

Methods: This randomized, double-blind, and placebo-controlled clinical trial was performed in 44 patients with a recent diagnosis of MI who underwent percutaneous coronary intervention.

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Cardiac cachexia (CC) adversely affects the lifestyle of heart failure (HF) patients. The current study examined the impact of melatonin cosupplementation and branched-chain amino acids (BCAAs) on quality of life (QoL), fatigue, and nutritional status in cachectic HF patients. In this trial, 84 CC patients were randomized to melatonin, BCAAs, or coadministration (both) as intervention groups and a control group over 8 weeks.

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Nutrition and probiotics supplementation are considered as nondrug strategies for the control of coronary artery disease (CAD). The aim of the present study was to investigate the interactive effects of probiotic supplementation and weight loss program on anthropometric and metabolic syndrome (MetS) indices in patients with CAD. A randomized, double-blind, placebo-controlled trial was performed in 44 overweight CAD patients.

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Article Synopsis
  • - Recent research indicates that angiogenic factors might influence the health of blood vessel linings, which is critical since endothelial dysfunction is a key issue in microvascular angina (MVA), prompting this study to evaluate these factors in MVA patients and assess the impact of metoprolol.
  • - The study involved 30 MVA patients and 20 healthy controls, measuring levels of angiopoietin-1, angiopoietin-2, and Tie-2 before and after a month of metoprolol treatment using enzyme-linked immunosorbent assay.
  • - Findings revealed higher levels of Ang-2 and Tie-2 in MVA patients compared to controls, but metoprolol did not significantly alter
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Background: Slow coronary flow (SCF) is a coronary artery disorder characterized with delayed opacification of epicardial coronary arteries without obstructive coronary disease. The pathophysiological mechanisms of SCF remain unclear. One of the possible mechanisms that may participate in the pathology of SCF is endothelial dysfunction related to the inflammatory process.

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Endothelial dysfunction which is manifested by the loss of nitric oxide bioavailability, is an increasingly recognized cause of cardiac syndrome X (CSX) and beta blockers are used for the treatment of this syndrome. Thus, the aim of this study was to investigate effects of metoprolol, as a beta blocker, on endothelial function in CSX patients. The study included 25 CSX patients (20 female/ 5 male, mean age: 55.

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Background: Data on frequency distribution of ABO-Rh blood groups in cardiac syndrome X (CSX) patients are not available. We aimed to investigate the distribution of ABO-Rh blood groups in these patients.

Materials And Methods: A total of 247 CSX patients' records were reviewed in a cross-sectional study from 2006 to 2010.

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