Development of dispersive solid-liquid extraction method based on organic polymers followed by deep eutectic solvents elution; application in extraction of some pesticides from milk samples prior to their determination by HPLC-MS/MS.

An effective extraction procedure based dispersive solid phase extraction was developed for the extraction of different pesticides (dimethoate, imidacloprid, pirimicarb, carbaryl, fenitrothion, hexythiazox, and phosalone) from milk samples. The analytes were determined by high performance liquid chromatography-tandem mass spectrometry. In this method, an organic polymer (polystyrene) was dissolved in a water-miscible organic solvent (tetrahydrofuran) and it was injected into the aqueous phase obtained from milk sample after deprotonation.

In-situ formation/decomposition of deep eutectic solvent during solidification of floating organic droplet-liquid-liquid microextraction method for the extraction of some antibiotics from honey prior to high performance liquid chromatography-tandem mass spectrometry.

A new liquid-liquid microextraction approach by applying a deep eutectic solvent was adopted for the extraction of four antibiotics (penicillin G, dihydrostreptomycin, enrofloxacin, and ciprofloxacin) from honey samples. The enriched analytes were analyzed by HPLC-MS/MS. The procedure was carried out by synthesis of tetrabutylammonium chloride: p-cresol deep eutectic solvent in the sample solution and then its decomposition in the presence of an acid.

A polymer-based dispersive solid phase extraction combined with deep eutectic solvent based-dispersive liquid-liquid microextraction for the determination of four hydroxylated polycyclic aromatic hydrocarbons from urine samples.

A new and efficient extraction procedure was proposed and used for the simultaneous extraction of four hydroxylated metabolites polycyclic aromatic hydrocarbons from urine samples. The extraction procedure was started by dissolving an organic polymer into a water-miscible organic solvent (iso-propanol) and its injection into the sample solution. The sorbent was re-precipitated in all parts of the solution as tiny particles and the analytes were adsorbed onto the sorbent.