Objectives: This study compared the anti-inflammatory effects of methylprednisolone (MP) and atorvastatin and analysed their influences on clinical variables in patients undergoing coronary revascularization.
Methods: Ninety patients with compromised left ventricular ejection fraction (≤30%) undergoing elective coronary surgery were equally randomized to one of three groups: statin group, treatment with atorvastatin (20 mg/day) 3 weeks before surgery; methylprednisolone group, a single shot of methylpredniosolone (10mg/kg); and control group.
Results: Postoperative IL-6 was higher in the control group when compared to the methylprednisolone and statin groups (p<0.
Cardiac surgeons are treating an increasing number of patients with diffuse coronary artery disease that requires the use of alternative surgical techniques. We present a patient who had a technically unsatisfactory endarterectomy of the left anterior descending coronary artery. We were left with only 3 segments of properly endarterectomized coronary bed areas, separated with totally disintegrated coronary bed portions.
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