Publications by authors named "Mio Kirino"
A 29-year-old woman had an episode of urticaria at the age of 17 while exercising after eating fried cuttlefish. For years thereafter, she experienced several episodes of urticaria after eating seafood. At the age of 29, she ate grilled seafood, including cuttlefish for supper after taking loxoprofen for lumbago.
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- Staphylococcus aureus (SA) is commonly found in skin lesions of atopic dermatitis (AD) and contributes to the disease's progression by releasing toxins that activate skin cells and increase levels of IL-18, leading to inflammation.
- Research shows a significant correlation between SA colony counts on the skin and IL-18 levels, linking these factors to the severity of AD in both human patients and DS-Nh mice, which serve as a model for studying the disease.
- CD25 +CD4 + regulatory T cells are identified as potentially key players in reducing AD symptoms by suppressing Th1 cell responses induced by IL-18, indicating a new avenue for AD treatment, particularly in the context of treatments affecting immune regulation.
Correlation of oral allergy syndrome due to plant-derived foods with pollen sensitization in Japan.
Ann Allergy Asthma Immunol
March 2010
Article Synopsis
- The study assessed oral allergy syndrome (OAS) in Japanese patients with pollen allergies, finding that 4.1% of pollen-sensitized individuals were diagnosed with OAS.
- The research revealed strong correlations between OAS prevalence and sensitization to alder pollen, particularly for foods like apple, peach, and melon.
- Overall, the findings suggest that pollen from the Betulaceae family, especially alder, plays a significant role in causing OAS among patients in Japan.
We report two cases of anaphylactic reactions to peach with negative result of ImmunoCAP to peach. Case 1 is a 35-year-old man, who felt an itch in his oral cavity immediately after ingesting a whole fresh peach. He rapidly developed generalized urticaria, dyspnea, vomiting, and loss of consciousness.
View Article and Find Full Text PDFBackground: Few cases of cashew nut (CN) allergy have been reported in Japan. We evaluated the clinical features of 4 cases with CN allergy and investigated the allergens involved.
Methods: In order to investigate the cross-reactivity between CN and pistachios, we performed ImmunoCAP inhibition tests using sera of 4 cases with positive histories of CN allergy and positive results of specific IgE measurement (ImmunoCAP) and skin prick tests.
Background: Oxidative stress has been implicated in the exacerbation of atopic dermatitis (AD).
Objective: We sought to investigate the pathophysiologic roles of inducible antioxidant heme oxygenase (HO) 1 in the development of AD.
Methods: Serum HO-1 levels of patients with AD (n = 100) and age-matched healthy control subjects (n = 72) were determined by means of ELISA.
Background/aim: Oral allergy syndrome (OAS) to plant foods is often caused by cross-reactivity to pollen. We investigated whether there was any significant correlation between sensitization to the pollen of alder and Japanese cedar flying off in spring and prevalence of OAS in Yokohama region.
Methods: We measured specific IgE antibodies (CAP-FEIA: CAP) against alder and Japanese cedar in 337 outpatients with skin allergy in 2005 (M:F=167:170, 33.
Article Synopsis
- The study investigates oral allergy syndrome (OAS) linked to plant-derived foods in Japan, analyzing clinical features and skin prick test results.
- It involved 118 patients, revealing that apple, peach, kiwi, and melon were the most common trigger foods, with a majority of patients also having associated pollen allergies.
- Results showed differing sensitivities based on the type of food, indicating a complex relationship between OAS symptoms and specific pollens.