Aim: To analyze the changes in scientific output relating to Leber congenital amaurosis (LCA) and forecast the study trends in this field.
Methods: All of the publications in the field of LCA from 2002 to 2022 were collected from Web of Science (WOS) database. We analyzed the quantity (number of publications), quality (citation and H-index) and development trends (relative research interest, RRI) of published LCA research over the last two decades.
Correction for 'Research on online monitoring of aircraft skin laser paint removal thickness using standard curve method and PCA-SVR based on LIBS' by Wenfeng Yang , , 2024, https://doi.org/10.1039/D4AY00872C.
View Article and Find Full Text PDFHigh-frequency pulse lasers, applied in the form of rapid scanning, act upon the surface of aircraft skin paint layers, thereby removing the paint layers, exhibiting characteristics of efficiency and eco-friendliness. Real-time monitoring of the paint removal effect and prevention of substrate damage necessitates the continuous monitoring of paint removal thickness. Combining Laser-Induced Breakdown Spectroscopy (LIBS) online monitoring technology enables laser-controlled paint removal under multiple effects coupling, meeting the requirements of airworthiness maintenance.
View Article and Find Full Text PDFPurpose: To assess the quantity and quality of global research on uveitis, visualize the research hotspots, and reveal the study trends in uveitis.
Methods: This bibliometric analysis was performed with the data obtained from the Web of Science core collection (WoSCC) database and Scopus. Bibliometrix and VOSviewer were used to analyze and visualize study trends and hotspots.
Aim: To investigate the research trend on refractive cataract surgery, compare the contributions of different countries, institutions, journals, and authors in the past 20y, and explore its potential research hotspots.
Methods: All publications were extracted relating to refractive cataract surgery from 2003 to 2022 from Web of Science. Document types were limited to original articles and reviews, and the language was limited to English.
Background: Since the poor prognosis of uveal melanoma with distant metastasis, we intended to screen out possible biomarkers for uveal melanoma metastasis risk and establish a nomogram model for predicting the risk of uveal melanoma (UVM) metastasis.
Methods: Two datasets of UVM (GSE84976, GSE22138) were selected. Data was analyzed by R language, CTD database and GEPIA.
Purpose: Our study aimed to make a bibliometric analysis on Sjögren's syndrome-related dry eye disease (SS-DED), explore its potential research hotspots, and provide critical information for future research interest and undeveloped topics in this field, which can benefit clinicians and researchers.
Methods: We extracted all publications relating to SS-DED from 2003 to 2022 from the Web of Science Core Collection database. Original articles and reviews in English were included.
Background: The literature on artificial intelligence (AI)-related topics has been expanding rapidly over the last two decades, showing that AI is a crucial force in advancing ophthalmology. This analysis aims to provide a dynamic and longitudinal bibliometric analysis of AI-related ophthalmic papers.
Methods: The Web of Science was searched to retrieve papers regarding the application of AI in ophthalmology published in the English language up to May 2022.
Purpose: To analyze publication trends for the past 20 years and identify potential research trends in the retinitis pigmentosa (RP) research field.
Methods: We extracted data from the Web of Science Core Collection and conducted a bibliometric analysis. All records related to RP from 2002 to 2021 were analyzed.
Front Cell Infect Microbiol
October 2022
Background: Sepsis is considered an intractable dysfunction that results from the disordered host immune response to uncontrolled infection. Even though the precise mechanism of sepsis remains unclear, scientific advances have highlighted the key role of various programmed cell death processes in the pathophysiology of sepsis. The current study aims to explore the worldwide research trend on programmed cell death in the setting of sepsis and assesses the achievements of publications from various countries, institutions, journals, and authors globally.
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
September 2022
Purpose: To explore the utility of the recovery time (RT) after temporal contrast adaptation in primary open-angle glaucoma (POAG) visual function analysis, especially in severe and end-stage glaucoma, by the Erlanger Flicker Test (EFT).
Methods: This study included 80 POAG eyes (45 subjects) and 20 normal eyes (20 subjects). POAG eyes were divided into 5 groups.
Introduction: Polypoidal choroidal vasculopathy (PCV) is a special subtype of AMD, which is one of the leading threats to vision health worldwide. At this time, many aspects of PCV, from how it works to potential treatments, remain a mystery. In this study, we explored the frontier researches and revealed the study trends within the study of PCV.
View Article and Find Full Text PDFBackground: Metastasis dominates the prognosis of eyelid sebaceous carcinoma (SC). This study aimed to explore risk factors for nodal metastasis and develop a nomogram to predict nodal metastasis in patients with eyelid SC.
Methods: A retrospective case-control study was performed, comprising 320 patients with eyelid SC.
Graefes Arch Clin Exp Ophthalmol
January 2022
Purpose: This study aims to evaluate the efficacy and safety of intralesional diode laser pretreatment for facilitating surgery for orbital venous malformations (OVMs).
Methods: This is a retrospective, non-comparative, interventional cohort involving 23 consecutive OVM patients undergoing intralesional laser pretreatment followed by surgical excision. The main outcome measures included volumetric changes, exophthalmometry, cosmesis, and symptom scores as well as treatment-related adverse events.
Retinoblastoma is the most common primary intraocular malignancy of childhood. Despite high survival and eye salvage as the result of various types of therapies, retinoblastoma remains a disease that places a considerable burden on developing countries. Our study attempted to analyse the research trends in retinoblastoma research and compare contributions from different countries, institutions, journals, and authors.
View Article and Find Full Text PDFBackground: Histone lactylation, a metabolic stress-related histone modification, plays an important role in the regulation of gene expression during M1 macrophage polarization. However, the role of histone lactylation in tumorigenesis remains unclear.
Results: Here, we show histone lactylation is elevated in tumors and is associated with poor prognosis of ocular melanoma.
Cutaneous melanoma is an aggressive malignancy with high heterogeneity. Several studies have been performed to identify cutaneous melanoma subtypes based on genomic profiling. However, few classifications based on assessments of immune-associated genes have limited clinical implications for cutaneous melanoma.
View Article and Find Full Text PDFUveal melanoma (UM) is the most prevalent primary intraocular malignancy in adults. Despite a high rate of success in controlling it as a local disease, it is prone to distant metastasis, and its mechanism of metastasis has not been elucidated. This study analyzes trends in UM research and compares contributions from different countries, regions, institutions and authors.
View Article and Find Full Text PDFOrbital invasion occurs in some periocular squamous cell carcinoma (SCC), compromising surgical outcomes, and prognoses of patients. To date, however, there are no validation studies on the clinical features related to orbital invasion in patients with periocular SCC. To explore clinical features that may be associated with orbital invasion and build a model for predicting the risk of orbital invasion.
View Article and Find Full Text PDFSmall ubiquitin-like modifier (SUMO), a critical regulatory modification protein, is involved in various biological processes, such as gene expression, genome maintenance and DNA damage repair (DDR). Numerous recent studies have revealed that disturbed SUMOylation and deSUMOylation homeostasis contribute to tumorigenesis. Abnormal alterations of key factors in the SUMO modification are closely related to cancer development and progression, indicating that the restoration of SUMOylation homeostasis may serve as a promising therapeutic strategy.
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