Publications by authors named "Minyeong Han"
Article Synopsis
- This study focused on how the adenosine A3 receptor (A3AR) influences the progression of metabolic dysfunction-associated steatotic liver disease (MASLD) through the regulation of immune cells, particularly pro-inflammatory Kupffer cells derived from monocytes (MoKCs).
- Researchers found that inhibiting A3AR, either through a drug called FM101 or by genetic deletion, significantly improved liver inflammation and fibrosis in model mice.
- The results suggest that targeting A3AR may offer a novel therapeutic approach for treating MASLD by inducing cell death (necroptosis) in harmful immune cells, thereby promoting a healthier liver environment.
