With the rapid advancement of the Internet of Things, network security has garnered increasing attention from researchers. Applying deep learning (DL) has significantly enhanced the performance of Network Intrusion Detection Systems (NIDSs). However, due to its complexity and "black box" problem, deploying DL-based NIDS models in practical scenarios poses several challenges, including model interpretability and being lightweight.
View Article and Find Full Text PDFIn modern society, environmental sustainability is a top priority as one of the most promising entities in the new energy sector. Electric vehicles (EVs) are rapidly gaining popularity due to their promise of better performance and comfort. Above all, they can help address the problem of urban air pollution.
View Article and Find Full Text PDFFree Radic Biol Med
March 2022
Colorectal cancer (CRC) is the third most commonly diagnosed malignancy and major cause of cancer death in the world. Ferroptosis is a recently identified type of regulated cell death. Increasing evidence has shown that ferroptosis plays an important regulatory role in the occurrence and development of cancer.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
January 2022
Background: Abnormal Cu(II) ions levels may affect many biological functions, and it is of great importance to detect Cu(II) ions in organisms.
Methods: Herein, we report a near-infrared (NIR) fluorescent probe EtRh-N-NH for the detection of Cu(II). In the probe structure, a rhodamine core was used, and a hydrazine group was employed as the responsive site.
In this paper, DSA-AAD-DA and DSA-TPDH-DA were prepared to effectively remove metal ions and cationic dyes from aqueous solution. The hydrazone structure was prepared by hydrazide-modified SA which captured metal ions selectively, and the remaining functional groups were used as active adsorption sites for cationic dyes. The thermodynamic parameter for the sorption demonstrated the process is endothermic and spontaneous.
View Article and Find Full Text PDFIn the present study, a new potential adsorbent for the separation and removal of heavy metal ions was prepared using hydrazide modification. Characterization of structural and chemical properties of the absorbent indicated the dialdehyde sodium alginate (DSA) grafted adipic acid dihydrazide (AAD) plays a crucial role. The adsorption process correlated well with Freundlich isotherm and pseudo-second-order kinetics models.
View Article and Find Full Text PDFInt J Biol Macromol
December 2021
Herein, a novel magnetic cross-linked chitosan CS-BA@FeO was rationally synthesized by cross-linked with epichlorohydrin and coated with FeO to the acylated chitosan, which was prepared by the reaction of chitosan with benzenetricarboxylic anhydride. The as-obtained absorbent was characterized by FTIR, XRD, VSM, TGA, TEM, BET, SEM and EDS. The results showed that the maximum adsorption capacities of CR and CV were 471.
View Article and Find Full Text PDFCancer cells can metabolize glutamine to replenish TCA cycle intermediates for cell survival. Glutaminase (GLS1) is over-expressed in multiple cancers, including colorectal cancer (CRC). However, the role of GLS1 in colorectal cancer development has not yet fully elucidated.
View Article and Find Full Text PDFBreast cancer has the highest incidence and mortality in the female population. Forkhead box M1 (FOXM1) known as a transcription factor is upregulated and associated with poor prognosis in a variety of cancers. However, the molecular mechanisms of FOXM1 on breast cancer progression are poorly understood.
View Article and Find Full Text PDFAims: Colorectal cancer (CRC) is the fourth leading cause of cancer-related mortality worldwide. Over-expression of tetraspanin 8 (TSPAN8) is related to the development and progression of CRC. Whether TSPAN8 plays a role in the growth of colorectal cancer and its epigenetic mechanisms regulated by Lysine Specific Demethylase 1 (LSD1) are still unknown.
View Article and Find Full Text PDFLysine demethylase 5B (KDM5B) is up-regulated in many cancers, including breast cancer. However, the underlying metabolic mechanisms of KDM5B on breast cancer progression are poorly understood. Here, we showed that KDM5B expression positively correlates with metastasis in breast cancer.
View Article and Find Full Text PDFA recombinant laccase from Trametes versicolor in Pichia methanolica was produced constitutively in a defined medium. The recombinant laccase was purified using ultrafiltration, anion-exchange chromatography, and gel filtration. The molecular weight of the purified laccase was estimated as 64 kDa by SDS-PAGE.
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