Publications by authors named "Minyan Zhuang"
In contrast to Type-II photodynamic therapy (PDT), Type-I PDT with less oxygen consumption has shown great potential against tumor hypoxia. However, there are limited strategies available for designing Type-I photosensitizers (PSs). Herein, we present a promising strategy for synthesizing Type-I PSs () using Tröger's base (TB) framework.
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- Evaluating peroxynitrite (ONOO) in living cells is challenging, but this study introduces a sensitive SERS sensor using modified gold nanoflowers (Au NFs/MAPE) for detection.
- The sensor operates by oxidizing aryl boric acid on the gold nanoflowers to release phenol, which alters the SERS spectrum, providing high selectivity and sensitivity for ONOO even in complex environments.
- With a detection limit of 0.48 μM, long-term stability, and excellent biocompatibility, this new sensor effectively monitors ONOO levels during oxidative stress, offering valuable insights into cell biochemistry.