Cutibacterium acnes thrives in low-oxygen environments and contributes to acne and antibiotic resistance by managing fatty acid production for membrane stability under these conditions.*
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The study focused on the acyl carrier protein (CaACP) in C. acnes, using NMR spectroscopy to reveal its structure and how it regulates fatty acid synthesis through specific residues.*
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Key findings showed that conformational changes within CaACP influence how fatty acids are processed, providing insights into C. acnes' survival strategies and potential targets for new treatments against antibiotic resistance.*