Publications by authors named "Minsu You"
Article Synopsis
- MeCP2 plays a significant role in cognitive dysfunction associated with psychiatric disorders and Alzheimer's disease, although its regulatory function in the striatum has been less studied.
- Research involved analyzing brain samples from APP/PS1 transgenic mice and human subjects to investigate molecular changes in the striatum using various techniques, including immunohistochemistry and behavioral tests.
- Findings revealed increased MeCP2 expression in the striatum during early and late stages of AD, with a link between MeCP2 dysregulation, cognitive deficits, and abnormal neuronal activity in the animal model, highlighting the importance of early intervention.
Coping is a strategic approach to dealing with stressful situations. Those who use proactive coping strategies tend to accept changes and act before changes are expected. In contrast, those who use reactive coping are less flexible and more likely to act in response to changes.
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