Sichuan Da Xue Xue Bao Yi Xue Ban
January 2015
Objective: To investigate the possible effects of apolipoprotein C I gene (APOC3) polymorphisms on plasma lipids in healthy adolescents with different body mass index (BMI).
Methods: Seven hundred and twenty three adolescents were divided into four groups according to BMI: group 1 CBMI= (17.80 +/- 0.
Objective: To investigate the role of the - 250G/A polymorphism in the promoter region of hepatic lipase gene (LIPC) on serum lipid profile and its interactions with a high-carbohydrate/low-fat (HC/LF) diet on serum lipid profiles in a young healthy Chinese population.
Methods: After a stabilization diet for seven days, fifty-six young healthy subjects (27 males, 29 females) were given the HC/LF diet for six days. The serum lipid profiles were analyzed of the twelve-hour fasting venous blood samples collected in the mornings of the first, the eighth and the fourteenth days.
Background: Diet induces changes in plasma lipid profiles, and the plasma lipid profiles vary among different genetic backgrounds.
Objectives: The aim of this study was to investigate how a high-carbohydrate (high-CHO) diet interacts with hepatic lipase G-250A promoter polymorphism to affect the ratios of plasma lipids and apolipoproteins (apo) in a young Chinese population.
Material And Methods: Experiments were conducted on 56 university students.
Both diet and genetic background have profound effects on plasma lipid profiles. It was hypothesized that a high carbohydrate (high-CHO) diet could affect the ratios of serum lipids and apolipoproteins (apo) differently in subjects with different genotypes of the C-514T hepatic lipase rs1800588 polymorphism. Fifty-six healthy university students were given a stabilization diet of 54.
View Article and Find Full Text PDFObjective: To investigate the effects of a high-carbohydrate diet on the lipid and apolipoprotein ratios in healthy young adults with different genotypes of the polymorphism at -75 site in the promoter region of the gene of apolipoprotein AI (APOA1).
Methods: Fifty-six subjects aged (22.89 +/- 1.
Objective: To investigate the effects of a low-fat and high-carbohydrate (LF-HC) diet on the physiological and biochemical indexes in healthy youth with different body mass index (BMI).
Methods: Seven overweight participants [BMI=(27.82 +/- 1.
In order to meet osmotic challenges in the gastrointestinal tract, enteric bacteria rapidly accumulate salts of glutamate and other weak organic acids. The ensuing transcriptional activation is mediated by unknown elements at sigma38 (rpoS)-dependent promoters. Here we identify DNA elements needed for high levels of transcription in the presence of salt and acetate and show that they are associated with the -35 regions of target promoters.
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