Acoustic effects of lamotrigine in pediatric patients with epilepsy.

The aim of this study was to investigate the acoustic effects of lamotrigine in pediatric epileptic patients. Newly diagnosed 52 pediatric epileptic patients were assessed standard speech test through a Computerized Speech Lab applied before the beginning of therapy with lamotrigine and 2months after dosage had been stabilized. The voice onset times for /t/, /k(h)/, /p'/ and /t'/ after the therapy and those for /p/, /k/, /p(h)/, /t(h)/ and /k'/ was not affected.