[Application of gene microarray to screen differential expression genes of Modic changes at vertebral endplates].

Objective: To identify differentially expressed genes in Modic changes by gene microarray method.

Methods: From August 2014 to December 2014, gene expression profiling analysis of 5 lumbar endplates with Modic changes and 5 control specimens without Modic changes were performed in Department of Orthopaedics, Zheng Linhai Second People's Hospital and Department of Orthopaedics, Shanghai Jiaotong University School of Medicine. The functional analysis (Gene Ontology and KEGG) of deregulated genes was carried out.

[Comparison among three cannulated screws and dynamic hip screw combined with antirotation screw for comminut- ed fractures of femoral neck].

Objective: To compare the effect of three cannulated screws and dynamic hip screw (DHS) combined with antirotation screw in treating patients with comminuted fractures of femoral neck.

Methods: From January 2008 to December 2012,67 patients with comminuted fractures of femoral neck were treated with three cannulated screws or DHS combined with antirotation screw. Among them, 36 patients were treated with DHS combined with antirotation screw including 24 males and 12 females with an average of 43.

[The evaluation of posterior ligament complex injury as well as the analysis of its effects in thoracic-lumbar fractures].

Objectives: To evaluate and analyze the role of posterior ligament complex (PLC) in determining therapeutic principle for traumatic thoracic-lumbar fracture.

Methods: From August 2005 to May 2008, 60 patients (38 male, 22 female) who suffered from the traumatic thoracic-lumbar fracture were carried out posterior operations. According to the Magerl traumatic thoracic-lumbar fracture classification system, these cases were classified to subtype A, B and C.