Publications by authors named "Minoru Sakairi"
Article Synopsis
- The study investigates the use of urinary catecholamine metabolites, especially vanillactic acid (VLA) and 3-methoxytyramine sulfate (MTS), in enhancing the diagnosis and risk assessment of neuroblastomas compared to traditional markers like homovanillic acid (HVA) and vanillylmandelic acid (VMA).
- Researchers analyzed urine samples from 68 neuroblastoma patients and 227 controls to establish a scoring system that categorizes participants into risk groups while adjusting for age.
- The newly developed scoring system showed significantly improved accuracy for diagnosis and risk assessment compared to conventional methods, indicating that VLA and MTS could replace HVA and VMA for
Urine is a complex liquid containing numerous small molecular metabolites. The ability to non-invasively test for cancer biomarkers in urine is especially beneficial for screening child patients. This study attempted to identify neuroblastoma biomarkers by comprehensively analysing urinary metabolite samples from children.
View Article and Find Full Text PDFReal-time explosive particle detection using a cyclone particle concentrator.
Rapid Commun Mass Spectrom
June 2014
Article Synopsis
- A new rapid detection method has been developed to identify explosive particles like TNT and RDX within just 3 seconds, significantly faster than traditional methods.
- The technique utilizes a cyclone particle concentrator that detaches particles from surfaces using air jets, vaporizes them, and then ionizes the vapor for analysis.
- This method enhances the detection limit to sub-ng levels and is promising for security applications due to its speed and efficiency in identifying trace explosives.
With the aim of improving security, a high-throughput portal system for detecting triacetone triperoxide (TATP) vapor emitted from passengers and luggage was developed. The portal system consists of a push-pull air sampler, an atmospheric-pressure chemical ionization (APCI) ion source, and an explosives detector based on mass spectrometry. To improve the sensitivity of the explosives detector, a novel linear ion trap mass spectrometer with wire electrodes (wire-LIT) is installed in the portal system.
View Article and Find Full Text PDFThe decrease of trichlorophenol by injecting oxidation catalyst into a municipal solid waste incinerator was monitored in real time. Direct sampling atmospheric pressure chemical ionization (APCI)/ion trap mass spectrometry (ITMS) was used for the real-time monitoring. The oxidation catalyst was iron oxide type, which exponentially reduced trichlorophenol emission.
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