Evaluation of histopathologic and histomorphometric changes of testicular tissue and gonadotropin levels following consumption of methylphenidate in male mice.

Background/aim: One of the most common psychiatric disorders in children is attention-deficit/hyperactivity disorder, which is treated extensively by methylphenidate. This study investigates the assessment of the effects of methylphenidate on histopathologic and histomorphometric changes of the testes and serum levels of gonadotropin in mice.

Materials And Methods: In this study, 36 adult male mice were used.

Histopathological evaluation of chronic gastritis with and without Helicobacter pylori colonization: a study from Iran.

Chronic gastritis is defined as the presence of chronic mucosal inflammatory changes leading eventually to mucosal atrophy and epithelial metaplasia. It is notable for distinct causal subgroups and for patterns of histological alterations that vary in different parts of the world. By far the most important aetiological association is chronic infection by the bacillus Helicobacter pylori (Hp).