Impact of Self-Management Clustered Care on Psychological and Birth Outcomes in Gestational Diabetes.

Purposes: To investigate the effects of a self-management-cluster-based pregnancy care model (SMB-CPCM) on the psychological status and delivery outcomes of pregnant women with gestational diabetes mellitus (GDM).

Patients And Methods: A total of 120 pregnant women with GDM who had been filed and had regular obstetric examinations in a tertiary-level hospital in Bengbu City between 1 April 2023 and 1 April 2024 were included in the study using the convenience sampling method. Sixty women each were grouped into a study group and a control group using the randomised numeric table method.

Effect of proton pump inhibitors versus histamine-2 receptor antagonists on acute kidney injury in septic patients at high risk for developing stress ulcers.

Background: To compare the effects of proton pump inhibitor (PPI) and histamine-2 receptor antagonist (H2RA) use on the occurrence of acute kidney injury (AKI) in septic patients at high risk for developing stress ulcers.

Methods: Using the Medical Information Mart for Intensive Care IV version 2.2 database, septic patients with high-risk factors for stress ulcers (i.

Exposure duration of ambient fine particulate matter determines the polarization of macrophages.

Ambient fine particulate matter (FPM) promotes airway inflammation and aggravates respiratory and cardiovascular diseases. Macrophage polarization plays an essential role in FPM-induced inflammation and tissue repair. The balance of pro-inflammatory M1-type and anti-inflammatory M2-type macrophages determines the fate of tissues and is involved in the pathogenesis of various FPM-induced diseases.

Risk Factors Associated with Multi-Drug Resistance in Neonatal Sepsis Caused by .

Background And Objective: An increasing number of cases of neonatal sepsis due to extended-spectrum beta-lactamase (ESBL)-producing multi-drug resistant (MDR) () have been reported worldwide. The aim of this study was to explore the risk factors associated with ESBL-producing MDR among neonates with culture-confirmed sepsis and thereby to help selection of appropriate empirical antibiotics.

Patients And Methods: All newborn infants with a confirmed pathogen isolated from blood or cerebrospinal fluid (CSF) from 2016 to 2021 were identified and those with infection were included in this analysis.

Pemetrexed long-term maintenance therapy for advanced severe lung cancer with long-term progression-free survival: a case report.

It is relatively rare to achieve a median progression-free survival (PFS) of 40 months with pemetrexed monotherapy maintenance, especially in patients with advanced and severe lung cancer. Here, we reported a case of advanced severe lung adenocarcinoma treated with pemetrexed monotherapy maintenance achieving long survival with a median PFS of 46 months. A 52-year-old female diagnosed with stage IV lung adenocarcinoma was tested for no targeted drug benefit in the driver gene.

Exploring the Spatiotemporal Evolution and Socioeconomic Determinants of PM2.5 Distribution and Its Hierarchical Management Policies in 366 Chinese Cities.

From 2013 to 2017, progress has been made by implementing the . Under the background of the (2018-2020), the pollution status of PM2.5, a typical air pollutant, has been the focus of continuous attention.

Early aEEG can predict neurodevelopmental outcomes at 12 to 18 month of age in VLBWI with necrotizing enterocolitis: a cohort study.

Background: Studies have shown that neurological damage is common in necrotizing enterocolitis (NEC) survivors. The purpose of the study was to investigate the predictive value of amplitude-integrated electroencephalogram (aEEG) for neurodevelopmental outcomes in preterm infants with NEC.

Methods: Infants with NEC were selected, and the control group was selected based on 1:1-2 pairing by gestational age.

Soluble Triggering Receptors Expressed on Myeloid Cells-1 as a Neonatal Ventilator-Associated Pneumonia Biomarker.

Background: Neonatal ventilator-associated pneumonia (NVAP) is one of the main infections acquired in hospitals, and soluble triggering receptors expressed on myeloid cells-1 (sTREM-1) are a TREM-1 subtype that can be released into the blood or bodily fluids during an infection.

Methods: The patients included in the present study were divided into three groups: the NVAP group, the first control group, and the second control group (n = 20, each). Children requiring respiratory treatment were assigned to the NVAP group, newborns who received mechanical ventilation and had neonatal respiratory distress syndrome were assigned to the first control group, and newborns with normal X-ray and electrocardiogram results but no non-pulmonary infection was assigned to the second control group.

Causing Neonatal Meningitis During 2001-2020: A Study in Eastern China.

Background And Objective: Neonatal meningitis (NM) caused by remains a major health problem in industrialized countries. Currently, information on the epidemiology and antimicrobial susceptibility patterns of NM in developing countries such as China is relatively scarce. Therefore, the present study investigated changes in the antimicrobial susceptibility of causing NM in a perinatal center in eastern China over the past 20 years.

Suspicious Plantar Lesion-A Case Report of Angiosarcoma.

Diabetic foot is one of the most common complications of diabetic mellitus (DM). This DM patient was admitted to our hospital presented with a 2-month history of plantar lesion. Shortly afterward, the patient appeared hemoptysis, respiratory failure, and multiple purpuric papules on his limbs.

Clinical Analysis of Severe Radiation Pneumonia.

Objective: The present study aims to discuss the clinical characteristics, factors, and treatment methods affecting the prognosis in patients with severe radiation pneumonia (RP).

Methods: The radiotherapy status, clinical features, imaging characteristics, laboratory examination results, treatment methods, and prognoses of 34 patients with severe RP treated in our department between January 2011 and July 2017 were retrospectively analyzed. The severe RP grading was based on the Common Terminology Criteria for Adverse Events version 4.

[Exposure of acute severe air pollution promotes inflammatory cell infiltration and increases the levels of proinflammatory cytokines and chemokines in lung tissues of rats].

Objective To observe the effect of acute severe air pollution exposure on cytokines and chemokines in lung tissues of rats and explore its significance. Methods During the period of severe air pollution in Beijing from December 17 to 22, 2016, rats were exposed to air pollution for 6 days, and then sacrificed on the 7th day. Lung tissues were taken and their histological changes were observed by HE staining.

Cavitation and fatal hemoptysis after immunotherapy for advanced lung adenocarcinoma: A case report.

Immune checkpoint inhibitor (ICI)-related massive hemoptysis with cavitation has rarely been identified. Here, we report a case of advanced lung adenocarcinoma with lethal bleeding after eight cycles of pembrolizumab. A 55-year-old male was diagnosed with stage IV non-small cell lung cancer (NSCLC).

Hyperosmotic Infusion and Oxidized Surfaces Are Essential for Biofilm Formation of From the Neonatal Intensive Care Unit.

is an opportunistic pathogen often implicated in bloodstream infections in the neonatal intensive care unit (NICU). This is assisted by its ability to form biofilms on indwelling central venous catheters (CVC), which are highly resistant to antibiotics and the immune system. We sought to understand the fundamentals of biofilm formation by in the NICU, using seventeen clinical isolates including the endemic NRCS-A clone and assessing nine commercial and two modified polystyrene surfaces.

Multi-Drug Resistant Causing Early-Onset Neonatal Sepsis - a Single Center Experience from China.

Background And Objective: Infections caused by extended-spectrum beta-lactamase (ESBL)-producing () have raised public-health concerns and are becoming a global health challenge. This study aimed to investigate changes in antimicrobial resistance of responsible for early-onset sepsis (EOS) in a perinatal center in eastern China.

Methods: Two periods, 2002 to 2008 and 2012 to 2018, were investigated.

Clinical analysis of a case of neonatal exfoliative esophagitis in an 18-day-old neonate.

Background: This study aims to provide guidance for clinical work through analysis of the clinical characteristics, endoscopic and pathological manifestations, diagnosis, and treatment of an 18-day-old neonate with exfoliative esophagitis.

Case Presentation: The patient presented with vomiting but the parents did not pay too much attention. The pathological report revealed numerous fibrinous exudative necrotic, and inflammatory cells, as well as a small amount of squamous epithelium.

[Analysis of pathogenic bacteria and drug resistance in neonatal purulent meningitis].

Objective: To study the clinical characteristics, pathogenic bacteria, and antibiotics resistance of neonatal purulent meningitis in order to provide the guide for early diagnosis and appropriate treatment.

Method: A retrospective review was performed and a total of 112 cases of neonatal purulent meningitis (male 64, female 58) were identified in the neonatal intensive care unit of Yuying Children's Hospital of Wenzhou Medical University seen from January 1, 2004 to December 31, 2013. The clinical information including pathogenic bacterial distribution, drug sensitivity, head imageology and therapeutic outcome were analyzed.

[Clinical analysis and follow-up of neonatal purulent meningitis caused by group B streptococcus].

Objective: To study the clinical characteristics, antibiotics sensitivity and outcome of group B streptococcus (GBS) meningitis in neonates in order to provide the guide for early diagnosis and appropriate treatment.

Method: A retrospective review was performed and a total of 13 cases of neonatal purulent meningitis caused by GBS were identified in the Neonatal Intensive Care Unit of Yuying Children's Hospital of Wenzhou Medical University from January 1, 2005 to May 31, 2013. The clinical characteristics, antibiotics sensitivity test results and outcome were analyzed.

[Clinical analysis of 31 cases of neonatal purulent meningitis caused by Escherichia coli].

Objective: Neonatal purulent meningitis is a severe infection responsible for high mortality and disabling sequelae. Escherichia coli is the main pathogen of neonatal purulent meningitis. This study explored the clinical characteristics and antibiotic resistance of Escherichia coli-induced neonatal meningitis.

[Changes of anti-Streptococcus pneumoniae status in rats with simulated weightlessness].

Objective: To study the changes of anti-Streptococcus pneumonia (SP) status in rats with simulated weightlessness, and therefore to provide theoretical basis for the aerospace medicine.

Methods: Thirty-two healthy male Wistar rats were randomly allocated into 4 groups: group A, the tail-suspension and SP group; group B, the tail-suspension without SP group; group C, the unsuspended but SP group; group D, the unsuspended and no SP group, with 8 rats in each. The tail-suspension method, i.

[The clinical characteristics and treatment of community outbreaks of the new influenza A (H1N1) infection].

Objective: To describe the clinical characteristics of 3 community outbreaks of the novel influenza A (H1N1), and to compare the treatment effects of the traditional Chinese medicine with or without Oseltamivir.

Method: The clinical records of 234 patients in 3 community outbreaks of the novel influenza A (H1N1) infection in June (n = 56), August (n = 96) and October (n = 82) of 2009 were analyzed, and the treatment effects of the traditional Chinese medicine with or without Oseltamivir were evaluated.

Results: The baseline characteristics, including age, temperature, indices of blood tests, hepatic and renal functions were distributed evenly between the 2 treatment groups.