Publications by authors named "Minke Lu"
Article Synopsis
- The gut microbiota plays a crucial role in maintaining the host's physiological functions through the metabolites it produces.
- In 2022, the gutMGene database was launched to help researchers understand the relationship between gut microbes, their metabolites, and host genes, categorizing these relationships as causal or correlational.
- The latest version, gutMGene v2.0, features an enhanced web interface for better user experience and includes metabolic reconstructions from human and mouse gut microbial genomes, available for free at http://bio-computing.hrbmu.edu.cn/gutmgene.
gutMGene (http://bio-annotation.cn/gutmgene), a manually curated database, aims at providing a comprehensive resource of target genes of gut microbes and microbial metabolites in humans and mice. Metagenomic sequencing of fecal samples has identified 3.
View Article and Find Full Text PDFA comprehensive review for gut microbes: technologies, interventions, metabolites and diseases.
Brief Funct Genomics
March 2021
Gut microbes have attracted much more attentions in the recent decade since their essential roles in the development of metabolic diseases, cancer and neurological diseases. Considerable evidence indicates that the metabolism of gut microbes exert influences on intestinal homeostasis and human diseases. Here, we first reviewed two mainstream sequencing technologies involving 16s rRNA sequencing and metagenomic sequencing for gut microbes, and data analysis methods assessing alpha and beta diversity.
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