Publications by authors named "Minke L Feenstra"

Article Synopsis
  • The study aimed to compare recovery quality in esophageal cancer patients receiving two types of pain relief: epidural and paravertebral analgesia, after minimally invasive esophagectomy (MIE).
  • The trial found that while both methods were effective, epidural analgesia provided better quality of recovery in the early postoperative days, though no significant differences were noted on postoperative day 3.
  • Ultimately, both analgesia techniques can be used in practice as they showed similar outcomes regarding complications and hospital stays.
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Background And Objective: Optimal pain management for esophagectomy facilitates prevention of postoperative complications such as pneumonia, but also chronic pain. Historically, multimodal intravenous analgesia was employed. In the last decades, regional anesthesia including epidural and paravertebral analgesia is frequently used.

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Study Objective: To evaluate all available evidence thus far on opioid based versus opioid-free anesthesia and its effect on acute and chronic postoperative pain.

Design: Systematic review and meta-analysis of randomized clinical trials.

Setting: Operating room, postoperative recovery room and ward.

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Background: Serum C-reactive protein (CRP) is commonly used by surgeons to raise suspicion of anastomotic leakage and other infectious complications, but most studies on optimal cut-off values are retrospective with a small sample of patients. The aim of this study was to determine the accuracy and optimal cut-off value of CRP for anastomotic leakage in patients following esophagectomy for cancer.

Materials And Methods: Consecutive minimally invasive esophagectomy for esophageal cancer patients was included in this prospective study.

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Background: Nasogastric tube (NGT) insertion is the standard of care in many hospitals after esophagectomy for gastric conduit decompression. An upper gastrointestinal contrast passage evaluation (UGI-CE) is a diagnostic test to evaluate passage through the gastric conduit. The authors hypothesized that introducing routine UGI-CE after esophagectomy results in earlier removal of the NGT and resumption of oral intake.

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Background: For esophagectomy, thoracic epidural analgesia (TEA) is the standard of care for perioperative pain management. Although effective, TEA is associated with moderate to serious adverse events such as hypotension and neurologic complications. Paravertebral analgesia (PVA) may be a safe alternative.

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Background: Influence of sarcopenia in combination with other body composition parameters and muscle strength on outcomes after oesophageal surgery for oesophageal cancer remains unclear. The objectives were (i) to describe the incidence of sarcopenia in relation to adipose tissue quantity and distribution and muscle strength; (ii) to evaluate if neoadjuvant chemoradiation (nCRTx) influences body composition and muscle strength; and (iii) to evaluate the influence of body composition and muscle strength on post-operative morbidity and long-term survival.

Methods: This retrospective study included patients with oesophageal cancer who received nCRTx followed by surgery between January 2011 and 2016.

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