Publications by authors named "Minkailou M"

Article Synopsis
  • Immune checkpoint inhibitors (ICIs) like pembrolizumab have notable clinical advantages but can cause serious side effects known as immune-related adverse events (irAEs), affecting various organ systems.
  • A case study of a female patient revealed that she experienced myxedema coma (MC) and adrenal insufficiency (AI) four months after stopping treatment with pembrolizumab, necessitating treatment with levothyroxine and hydrocortisone.
  • This highlights the need for careful monitoring of patients on ICIs for potential endocrine disorders, as they can lead to severe health complications if not detected early.
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In March 2021, in the framework of a partnership between the Geneva University Hospitals (HUG), the Santé Diabète Organization and the Ministry of Health of Mali, a 4-day workshop training course was organized with the objective of strengthening the skills of caregivers in Therapeutic Patient Education (TPE) for children and young people with type 1 diabetes. To ensure interprofessionalism, physician-nurse pairs already working together in health structures in 7 regions of Mali participated in the training. Beyond complementarity between health professionals, the aim was to cope with the realities of the Malian health system.

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Aims: Determine incidence, prevalence and mortality of Type 1 diabetes (T1D) in children and youth <25 years (y) in Mali during the first 10 years of the Santé Diabète/Life for a Child program.

Methods: Data were collected from the prospective program register. Diagnosis of T1D was clinical, based on presentation, clinical features, immediate requirement for insulin, and no suggestion of other diabetes types.

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Introduction: Hyperprolactinemia, which is a supra-physiological secretion of prolactin, is the most common anterior pituitary disorder encountered in clinical practice. Its incidence and prevalence are poorly defined in Africa and the rest of the world. The study the clinical, paraclinical, etiological and therapeutic aspects of hyperprolactinemia at the Mali hospital.

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Introduction: Dysthyroidism (hyperthyroidism or hypothyroidism) in children and adolescents is much rarer than in adults. The purpose of our study was to study the epidemiological, clinical, paraclinical, etiological and etiological aspects and to specify the therapeutic and evolutionary modalities of this condition.

Method: This was a five-year descriptive, retrospective and prospective study of children and adolescents under 18 years of age with dysthyroidism.

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