Holding on and letting go: identity and acculturation among Chinese immigrants.

This study addresses the general question of whether ethnic identity and general acculturation would prove unique discriminators of quality of life for Chinese immigrants. Eighty-three Chinese immigrants served as participants. Survey data were collected regarding acculturation, Asian identity, and quality of life; observers provided ratings of certain home environment characteristics; and participants responded to open-ended interview questions about their immigration experiences that allowed for qualitative data analysis on perspectives of culture.

Immunochemical versus guaiac occult blood stool tests: results of a community-based screening program.

This study was designed to investigate two guaiac-based and one immunochemical faecal occult blood test in a community screening program. A total of 39,000 test kits consisting of Hemoccult II, Hemoccult Sensa and HemeSelect were distributed and of these 8933 (23%) were returned for testing. Follow-up contact with 1165 individuals who tested positive on at least one of the nine test slides was successful in 1076 cases (92.

Massive screening for colorectal cancer. A single institution's public commitment.

Data from three massive screening programs for the detection of colorectal cancer and adenomatous polyps were reproducible through the collaboration of several departments at Roswell Park Memorial Institute, Buffalo, NY. The majority of carcinomas detected had demonstrated no lymph node metastases. The percentage of screenees with positive stool occult blood tests discovered to have colorectal cancer and adenomatous polyps was 19%, 24%, and 21% in 1982, 1984, and 1987, respectively.

Taxonomy of family life styles: III. Replication with families with severely mentally retarded children.

The home environment and behavior of 97 families with severely mentally retarded children was examined in order to determine the presence of family types. Cluster analysis was performed on 16 measures of proximal home environment. Five unique family clusters were identified: cohesive, control-oriented, responsive-to-child, moral-religious-oriented, nonachievement-oriented, and achievement-oriented.

Direction of effects: family life styles and behavior of TMR children.

The direction of effects were examined between TMR children and their families in three previously determined family types: cohesive, harmonious; control oriented, somewhat unharmonious; and child-oriented, expressive. Child variables studied were measures of adaptive behavior, psychosocial adjustment, and self-esteem. Family variables included measures of cohesion and conflict, provision of cognitive stimulation, parental warmth and affection, quality of the residential environment, and openness with the interviewer.

Automated platelet-sizing parameters on a normal population.

The quantitation of platelets in peripheral blood is a well-recognized tool. However, other platelet parameters that recently have become available on a routine basis with the introduction of automated cell sizers may become increasingly important in evaluating the integrity of the thrombocytic function. These parameters include mean platelet volume (MPV) and platelet-crit (PCT).

Enhancement of the indirect anti-platelet antibody test and its application to platelet immunology.

Comparisons in the same patients of platelet-bound anti-platelet antibody (APA) levels (direct test) with serum APA levels (indirect test) frequently do not give the same results. Indirect test results frequently are negative or marginally elevated even though platelet-bound antibody is greatly increased on direct testing. The most likely cause for these differences between the two tests is insufficient binding of serum antibody to test platelets in vitro.

Taxonomy of family life styles: II. Homes with slow-learning children.

A battery of instruments dealing with family social environment and family and child characteristics and behavior was administered to 218 families with slow-learning children in EMR and educably handicapped programs. Cluster analysis was performed on family environment variables. Seven unique family clusters, each with distinctive patterns of characteristics, were identified: child-oriented, cohesive; learning-oriented, high residential quality; low disclosure, unharmonious; disadvantaged, noncohesive; achievement-oriented, low residential quality; expression-oriented with few sociocultural interests; and outerdirected with little achievement-orientation.

Predicting retarded students' short-term growth from home environment.

This investigation sought to determine whether change in mentally retarded students' developmental status and adjustment could be predicted by variables of the psychological home environment for periods of one and two years. Over 120 trainable mentally retarded (TMR) and over 220 educable mentally retarded and educationally handicapped (EMR-EH) children were subjects. Annual interviews were conducted in the homes.

Reciprocal relationship between home environment and development of TMR adolescents.

The reciprocal relationship between home environment and social competency of 112 TMR adolescents was examined over a period of 3 years. Assessment of home environment included child-rearing attitudes, educationally relevant stimuli and opportunities available at home, and general psychosocial climate among family members. Measures of social competency included the child's adaptive behavior, psychosocial adjustment, and self-concept.

Taxonomy of family life styles: I. Homes with TMR children.

A battery of instruments dealing with family social environment and family and child characteristics and behavior was administered to 115 families with children in TMR classes. Cluster analysis was performed on the social environment variables. Five distinctive clusters of families, each with distinctive patterns of characteristics, were identified: cohesive, harmonious; control-oriented, somewhat unharmonious; low-disclosure, unharmonious; child-oriented, expressive; and disadvantaged, low morale.

Relationship between home environment and school adjustment of TMR children.

The relationship between the home environment and school adjustment of 104 TMR children was examined. Assessment of home environment included measurement of environmental process variables with Caldwell's HOME Inventory and psychosocial climate with Moos, Insel, and Humphrey's Family Environment Scale. Certain child-rearing attitudes and relevant demographic characteristics were also investigated.

Coagulation factors in renal adenocarcinoma.

Coagulation factors, including plasma fibrinogen, serum fibrinogen-fibrin degradation products, platelet counts and prothrombin times, were studied in patients with renal adenocarcinoma. Plasma fibrinogen levels were elevated and correlated with tumor stage, disease activity and therapy. Fibrinogen-fibrin degradation product levels also were elevated, although such elevations did not correlate with other parameters.

Progestational agents and blood coagulation. VIII. Effect of low-dose, alternate-day, estrogen-progestin combinations on blood coagulation factors in man, with a special note on the effect of freezing of blood samples.

Changes in the blood coagulation system were studied in three groups of 20 patients each. The first group received 0.5 mg.

Progestational agents and blood coagulation. VII. Thromboembolic and other complications of oral contraceptive therapy in relationship to pretreatment levels of blood coagulation factors: summary report of a ten-year study.

During a ten-year period, 348 women were studied for a total of 5,877 patient months in four separate studies relating oral contraceptives to changes in hematologic parameters. Significant increases in certain factors of the blood coagulation and fibrinolysin systems (factors I,II,VII,VIII,IX, and X and plasminogen) were observed in the treated groups. Severe complications developed in four patients.

Effect of galactose and sugar substitutes on blood insulin levels in normal and obese individuals.

Eighteen male patients between the ages of 25 and 50 were given on a double blind randomized basis (A) 40 gms. galactose (B) 50 gms. arabinogalactan and 0.

Clinical and experimental studies on adenine, various nucleosides and their analogs in hematology.

In red blood cells as well as in platelets there appears to be a decrease in adenine nucleotides during storage under blood bank conditions. This can be decreased by use of anticoagulant preservatives with higher phosphate content than the standard ACD solution, through the addition of adenine and inosine. Maintenance of higher ATP levels appears to be related to longer circulating life span after transfusion into patients in the case of red blood cells but not platelets.

Heparin and chemotherapy in the management of inoperable lung carcinoma.

Twenty-eight patients with inoperable or metastatic carcinoma of the lung who failed to respond to conventional chemotherapy and/or radiotherapy were entered in this study. All of them received repeated courses of multiple chemotherapy (cyclophosphamide, 5-fluorouracil, 6-thioguanine, methotrexate, and vincristine) with or without concurrent intravenous heparin anticoagulation. No tumor regression was noted in any of the 14 patients who received the multiple chemotherapy only.

Studies on the prevention of respiratory distress syndrome of infants due to hyaline membrane disease with plasminogen.

Hyaline membrane disease (HMD) is leading single cause of death of newborn, premature infants. The "hyaline membranes" consist chiefly of fibrin. The clinical manifestation of HMD is the respiratory distress syndrome (RDS).

Thromboembolic complications of oral contraceptive therapy.

During a ten-year period, 348 women were studied for a total of 5877 patient months for changes in hematologic parameters induced by oral contraceptives. Significant increases were observed in Factors I, II, VII, VIII, IX, X and plasminogen. Severe complications developed in four patients.

Causes of death in cancer patients.

Causes of death in the year 1970 were analyzed retrospectively on the basis of clinical and pathologic reports of 506 cases in the Roswell Park Memorial Institute and Hospital. The single major cause of death was infection (36%), which was also a contributory factor in an additional 68% of the cases. Other important causes of death were hemorrhagic and thromboembolic phenomena (18%), which also were contributory factors in an additional 43%.