Alterations in Methionine Cycle and Wnt/MAPK Signaling Associated with HMBi-Induced Cashmere Growth in Goats.

Methionine (Met) was the first limiting amino acid identified in cashmere goats, and 2-hydroxy-4-(methylthio) butanoic acid isopropyl ester (HMBi) can effectively provide Met and encourage cashmere growth in goats. However, existing studies have primarily centered on the trait of cashmere growth and have not delved into the underlying molecular and physiological mechanisms by which HMBi promotes cashmere growth in goats. In the present study, we combined metabolomic and transcriptomic approaches to reveal the effects of HMBi supplementation and its impact on the gene expressions and metabolic profiles within the skin tissue of Liaoning cashmere goats.

Waveguide Microactuators Self-Rolled Around an Optical Fiber Taper.

Precisely capturing and manipulating microscale objects, such as individual cells and microorganisms, is fundamental to advancements in biomedical research and microrobotics. Photoactuators based on optical fibers serving as flexible, unobstructed waveguides are well-suited for these operations, particularly in confined locations where free-space illumination is impractical. However, integrating optical fibers with microscale actuators poses significant challenges due to size mismatch, resulting in slow responses inadequate for handling motile micro-objects.

Electrostatic Spray Ionization-Mass Spectrometry for Direct and Fast Wine Characterization.

Due to the globally existed and economically motivated adulteration including mislabeling and/or blending, fast wine characterization is important in wine industry. Herein, we developed an electrostatic spray ionization-mass spectrometry (ESTASI-MS)-based method to distinguish wines. Wine samples were directly analyzed by ESTASI-MS without any pretreatment.