Publications by authors named "Minjie Chen"

Objective: The aim of this study is to develop, implement the precise reservation path (PRP) and investigate its prediction function for scheduling shunting patients for specialist appointment registration in Shanghai, China.

Design: The PRP system was built on the hospital's existing information system, integrated with WeChat (WeCom) for user convenience. The outcome analysis employed a mixed-methods approach, integrating quantitative analysis with statistical and machine learning techniques, including multivariate logistic regression, random forest (RF) and artificial neural network (ANN) analysis.

View Article and Find Full Text PDF

Dewatering of waste activated sludge is a necessary step for achieving subsequent reduction, stabilization, and resource utilization. In this study, Fe/periodate (PI) coupled with polyoxometalates (POMs) conditioning was tested for realizing sludge deep dewatering. After the addition of POMs (0.

View Article and Find Full Text PDF

Perfluorohexane sulfonate (PFHxS) has been listed as a new persistent organic pollutant since 2022. Although the production and use of PFHxS are now restricted, it remains highly persistent in aquatic environments for decades. However, so far research about the toxic effects on early-life exposure of PFHxS and underlying mechanisms are still limited.

View Article and Find Full Text PDF

Purpose: This study aims to evaluate the efficacy of tip-flexible suctioning ureteral access sheath (TFS-UAS) compared to traditional ureteral access sheath (T-UAS) in flexible ureteroscopic lithotripsy (FURL) for unilateral upper urinary tract calculi.

Methods: The study retrospectively compared outcomes from 103 cases using TFS-UAS and 138 using T-UAS treated with FURL for unilateral upper urinary tract calculi from January to October 2023. Assessed parameters included patient demographics, stone characteristics, preoperative urine cultures, ureteral pre-stenting, comorbidities, procedure time, stone-free rate (SFR), utilization of stone retrieval baskets, and postoperative Systemic Inflammatory Response Syndrome (SIRS) rates.

View Article and Find Full Text PDF
Article Synopsis
  • * Edible multifunctional capsule robots have shown promise over the past two decades for advancing the monitoring, diagnosis, and treatment of intestinal conditions.
  • * This review discusses the relationship between the gut microbiome and diseases, details the design of these capsule robots, explores their biomedical applications, and addresses the challenges and future prospects in their development.
View Article and Find Full Text PDF

Introduction: The elevated mortality and hospitalization rates among hemodialysis (HD) patients underscore the necessity for the development of accurate predictive tools. This study developed two models for predicting all-cause mortality and time to death-one using a comprehensive database and another simpler model based on demographic and clinical data without laboratory tests.

Method: A retrospective cohort study was conducted from January 2017 to June 2023.

View Article and Find Full Text PDF

Cholangiocarcinoma (CCA) is a rare but highly invasive cancer, with its incidence rising in recent years. Currently, surgery remains the most definitive therapeutic option for CCA. However, similar to other malignancies, most CCA patients are not eligible for surgical intervention at the time of diagnosis.

View Article and Find Full Text PDF

Purpose: While lacrimal gland removal is commonly used in animal models to replicate dry eye disease, research into systematically monitoring dry eye disease's longitudinal pathological changes is limited. In vivo confocal microscopy (Heidelberg Retina Tomograph 3 with a Rostock Cornea Module, Heidelberg Engineering Inc., Franklin, MA) can non-invasively reveal corneal histopathological structures.

View Article and Find Full Text PDF

The advent of PD1/PD-L1 inhibitors has significantly transformed the therapeutic landscape for clear cell renal cell carcinoma (ccRCC). This review provides an in-depth analysis of the biological functions and regulatory mechanisms of PD1 and PD-L1 in ccRCC, emphasizing their role in tumor immune evasion. We comprehensively evaluate the clinical efficacy and safety profiles of PD1/PD-L1 inhibitors, such as Nivolumab and Pembrolizumab, through a critical examination of recent clinical trial data.

View Article and Find Full Text PDF

Objectives: The aim of this study was to explore inflammation of soft tissue around the upper third molar as a prevalent cause of limited mouth opening, identify the clinical and radiographic features, and summarize the therapeutic effectiveness of tooth extraction.

Materials And Methods: A retrospective analysis of data from 264 patients with limited mouth opening over the last five years was performed.

Results: Among the 264 patients, 24 (9.

View Article and Find Full Text PDF

Clear cell renal cell carcinoma (ccRCC) is a common kidney cancer with subtle early symptoms, high recurrence rates, and low sensitivity to traditional treatments like radiotherapy and chemotherapy. Identifying novel therapeutic targets is critical. The expression level of adenylate kinases 7 (AK7) in ccRCC was examined by the TCGAportal and UALCAN databases.

View Article and Find Full Text PDF

The interaction between the immune system and the tumor matrix has a huge impact on the progression and treatment of cancer. This paper summarizes and discusses the crosstalk between T cells and cancer-associated fibroblasts (CAFs). CAFs can also produce inhibitors that counteract the function of T cells and promote tumor immune escape, while T cells can also engage in complex two-way interactions with CAFs through direct cell contact, the exchange of soluble factors such as cytokines, and the remodeling of the extracellular matrix.

View Article and Find Full Text PDF

Background: Inferior alveolar nerve (IAN) injury is one of the complications of impacted lower mandibular third molar (LM3) extraction. Given the unknown prognosis of IAN injuries and limited treatment options, it is critical to understand the risk factors of IAN injury before LM3 extraction.

Purpose: The purpose of the study was to identify risk factors associated with IAN injury after LM3 extraction.

View Article and Find Full Text PDF

Background: Neuroendocrine carcinoma (NEC) of the extrahepatic bile duct is very rare, and the treatment and prognosis are unclear. Herein, we report the case of a middle-aged female with primary large cell NEC (LCNEC) of the common hepatic duct combined with distal cholangiocarcinoma (dCCA). Additionally, after a review of the relevant literature, we summarize and compare mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) and pure NEC to provide a reference for selecting the appropriate treatment and predicting the prognosis of this rare disease.

View Article and Find Full Text PDF
Article Synopsis
  • - Cholangiocarcinoma (CCA) is a rare but aggressive cancer with rising incidence rates, and while surgical resection is the best treatment, many patients are not eligible for surgery at diagnosis.
  • - The standard chemotherapy for advanced CCA involves a combination of gemcitabine and cisplatin, but resistance to treatment often limits effectiveness.
  • - Recent research highlights the potential of immune checkpoint inhibitors, specifically those targeting PD1/PD-L1, to improve outcomes when used alongside chemotherapy, leading to ongoing studies on their role in CCA treatment.
View Article and Find Full Text PDF

The selective hydrogenation of furfural (FFA) to furfuryl alcohol (FA) is regarded as attractive transformation to achieve the sustainable synthesis of value-added chemicals from biomass resources. However, the conventional supported catalysts are significantly restricted by their narrow pore size, ununiform dispersion and easy leaching or aggregation of catalytic sites. Herein, we designed hollow UiO-66-NH as the support to encapsulate Pd nanoparticles (Pd@H-UiO-66-NH) to achieve the highly active and selective conversion of FFA to FA.

View Article and Find Full Text PDF

Repair strategies for injured peripheral nerve have achieved great progresses in recent years. However, the clinical outcomes remain unsatisfactory. Recent studies have found that exosomes secreted by dental pulp stem cells (DPSC-exos) have great potential for applications in nerve repair.

View Article and Find Full Text PDF

This study evaluated the feasibility of simultaneous temporomandibular joint (TMJ) arthroscopy and orthognathic surgery as a new treatment strategy for anterior disc displacement without reduction (ADDwoR) patients with severe jaw deformities. Twelve ADDwoR patients with facial deformities who underwent arthroscopy and orthognathic surgery between September 2015 and December 2019 were retrospectively evaluated. Pre- and postoperative maximum incisal opening (MIO) and joint pain were recorded.

View Article and Find Full Text PDF

The prognosis of peripheral nerve injury (PNI) is usually poor, and currently, there is no effective treatment for PNI. Studies have shown that exosomes derived from mesenchymal stem cells could promote nerve regeneration by optimizing the function of endogenous Schwann cells (SCs), while the mechanism is unclear. Autophagy, a highly conserved intracellular catabolic process responsible for maintaining cellular homeostasis, has been proved to be involved in the regulation of nerve repair after injury.

View Article and Find Full Text PDF
Article Synopsis
  • Trigeminal neuralgia (TN) is a common nerve disorder affecting the facial area, with unclear causes and mechanisms behind it.
  • The study aimed to explore cell interactions in TN, focusing on how demyelination impacts the trigeminal ganglion, and to discover new target genes and pathways involved in the condition.
  • Findings indicated that the trigeminal ganglion influences Schwann cell behavior through various interactions, suggesting that compounds like ferroptosis might play a role in demyelination, thereby offering new insights for further research and potential drug development.
View Article and Find Full Text PDF

Bioactive constituents from Rhodiola rosea L. show a myriad of pharmacological effects on diverse diseases. Rosavin has been linked to reduced osteoclastogenesis, while its role in regulating osteogenesis remains unclear.

View Article and Find Full Text PDF

Objectives: The objective of the retrospective study was to explore whether the use of a modified alveolar ridge preservation technique impacts osteogenesis on the distal surface of the second molar after mandibular third molar (M3) extraction.

Materials And Methods: A total of 54 patients were enrolled in this study and divided into three different groups, including modified alveolar ridge preservation (MARP) group, traditional tooth extraction (TRA) group, and classical guided bone regeneration (GBR) group. In this study, MARP was designed with the highlights of the preservation of the alveolar bone superior and lingual to M3.

View Article and Find Full Text PDF

Objective: The prevalence of mental distress has been noted in shelter hospitals set up for COVID-19. Potential risk demographic and hospitalization factors were screened. We also aimed to determine whether humanistic care established in the shelter hospital was effective in ameliorating mental distress.

View Article and Find Full Text PDF