Serotype distribution and clinical characteristics of Group B Streptococcus Bacteremia in nonpregnant adults: a 15-Year Multicenter Study in Korea.

Background: Group B Streptococcus (GBS) bacteremia in nonpregnant adults is of increasing concern, particularly among the elderly in underlying conditions. This study analyzed the serotype distribution, antimicrobial resistance patterns, and clinical characteristics of GBS bacteremia in nonpregnant adults over a 15-year period in two tertiary hospitals in Korea.

Methods: From 2007 to 2021, patients aged ≥ 19 years with GBS bacteremia were identified via retrospective electronic medical record review.

Epiretinal Membrane: Correlations Among Clinical, Immunohistochemical, and Biochemical Features and Their Prognostic Implications.

Purpose: To investigate correlations among clinical, immunohistochemical, and biochemical characteristics of epiretinal membranes (ERMs) and their prognostic implications.

Methods: This prospective study included 120 patients with idiopathic ERM who underwent vitrectomy. Preoperative and postoperative best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) were measured.

Chemometrics for estimating the fermentation and quality properties of kimchi based on hyperspectral image analysis.

Kimchi is a traditional Korean dish made from fermenting vegetables. The fermentation process is crucial for enhancing its quality and flavor during storage. Approaches such as hyperspectral imaging (HSI) and chemometrics (PLS, partial least square; SVR, support vector regression) including principal component analysis (PCA), and 2-dimensional correlation spectroscopy (2D-COS) can detect key physical and chemical components and changes in total soluble solids (TSS), pH, titratable acidity (TA), salinity, and lactic acid bacteria (LAB).

Nucleated red blood cells for characterization of systemic inflammatory response syndrome in dogs.

Background: Nucleated red blood cells (nRBCs) are increased by disease processes and hematopoietic stress.

Objectives: To evaluate the utility of nRBCs as a marker of disease severity and prognosis in dogs with systemic inflammatory response syndrome (SIRS).

Animals: Sixty-two client-owned dogs met the criteria of SIRS without anemia.

Overdiagnosis of dental caries in South Korea: a pseudo-patient study.

Background: To evaluates the tendency of South Korean dentists to over-diagnose clinically healthy teeth in pseudo-patients.

Methods: We conducted a pseudo-patient, cross-sectional study in 196 private dental clinics with 58 pseudo-patients in South Korea between August and December 2018. Trained pseudo-patients with no previous oral diseases, including dental caries, diagnosed by two experienced dentists, were sent to each dental clinic.

Evaluating the capacity of magnetic ionic liquids for separation and concentration of non-enveloped viral particles and free viral genomic RNA.

Magnetic ionic liquids (MILs) have proven effective as capture reagents for foodborne bacterial pathogens; however, there are currently no published studies regarding their use with foodborne, non-enveloped viruses. In this study, a protocol was evaluated for capture and recovery of bacteriophage MS2, a human norovirus surrogate, and purified viral genomic single stranded RNA (ssRNA) from an aqueous suspension using MILs. Transition metal-based MILs showed similar capture and recovery efficiency for both targets.

Efficacy of High-Dose Synbiotic Additives for Deoxynivalenol Detoxification: Effects on Blood Biochemistry, Histology, and Intestinal Microbiome in Weaned Piglets.

Deoxynivalenol (DON) is a common mycotoxin observed in cereal grains, and feed contamination poses health risks to pigs. Biological antidotes, such as synbiotics (SYNs), have garnered attention for mitigating DON toxicity. This study aimed to assess the efficacy of SYNs by comparing the blood biochemistry, histology, and gut microbiome of weaned piglets.

-3 Fatty Acids in Seafood Influence the Association Between the Composite Dietary Antioxidant Index and Depression: A Community-Based Prospective Cohort Study.

Accumulating evidence suggests that seafood and its components, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are associated with mental health. However, little is known regarding whether the status of -3 polyunsaturated fatty acids (PUFAs) modify the effect of dietary antioxidants on depression. The main purpose of study is to investigate longitudinal associations between seafood consumption and depression among 2564 participants aged 40-69 years using data from the Korean Genome and Epidemiology Study.

In Vitro Modeling of Atherosclerosis Using iPSC-Derived Blood Vessel Organoids.

As modeling of atherosclerosis requires recapitulating complex interactions with vasculature and immune cells, previous in vitro models have limitations due to their insufficient 3D vascular structures. However, induced pluripotent stem cell-derived blood vessel organoids (BVOs) are applicable for modeling vascular diseases, containing multiple cell types, including endothelial and vascular smooth muscle cells self-assembled into a blood vessel structure. Atherosclerotic BVOs with a microenvironment associated with atherogenesis, such as shear stress, low-density lipoprotein, pro-inflammatory cytokine, and monocyte co-culture are successfully developed.

Dynamics of blood Taurine concentration and its correlation with nutritional and physiological status during the fattening period of Japanese black cattle.

Taurine, biosynthesized from methionine or cysteine in the liver, plays a crucial regulatory role in bile acid conjugation, antioxidant effects, and glucose and cholesterol metabolism. This may influence the metabolic changes associated with fat accumulation in beef cattle. However, the physiological role of taurine in this species has not been fully elucidated.

Selective denoising autoencoder for classification of noisy gas mixtures using 2D transition metal dichalcogenides.

Electronic nose (E-nose) technology, which is composed of an array of chemical sensors and pattern recognition, has been widely utilized for the quantitative classification of gas mixtures. However, for the practical use of E-nose in real-industry, advanced algorithms are necessary to handle the noise in sensing data caused by various environmental variables. In order to achieve precise measurements even in real-world environments, it is necessary to denoise and classify noisy sensing data.

Assessment of Nonmass Lesions Detected with Screening Breast US Based on Mammographic Findings.

Background Breast nonmass lesions (NMLs) are observed at screening and diagnostic US. However, knowledge is limited on imaging features of NMLs at screening US. Purpose To identify features of NMLs at screening US that are suspicious for malignancy based on mammographic findings.

An integrated view of the structure and function of the human 4D nucleome.

The dynamic three-dimensional (3D) organization of the human genome (the "4D Nucleome") is closely linked to genome function. Here, we integrate a wide variety of genomic data generated by the 4D Nucleome Project to provide a detailed view of human 3D genome organization in widely used embryonic stem cells (H1-hESCs) and immortalized fibroblasts (HFFc6). We provide extensive benchmarking of 3D genome mapping assays and integrate these diverse datasets to annotate spatial genomic features across scales.

Race and Ethnicity Impacts Patient-Reported Outcomes in Implant-Based Breast Reconstruction.

Background: Addressing social determinants of health is critical in achieving health equity, and of the many determinants, race and ethnicity are key contributors in postmastectomy breast reconstruction. The purpose of this study was to investigate the impact of race and ethnicity on patient-reported outcomes (PROs) after implant-based breast reconstruction (IBBR) and to provide reference values for each cohort.

Methods: We identified all patients who underwent IBBR between January 2017 and August 2022 and completed the BREAST-Q longitudinally.

Risk and clinical characteristics of spinal cord compression across different mucopolysaccharidosis types: A retrospective cohort study.

In patients with mucopolysaccharidosis (MPS), the accumulation of glycosaminoglycans leads to various complications, including spinal cord compression (SCC). Although SCC is a well-known complication in MPS, data comparing its clinical features across different MPS types remain limited. This study aimed to investigate the timing, location, and underlying causes of SCC in MPS, as well as to compare the risk and clinical characteristics by MPS type.

Immunostimulatory Activity of a Mixture of , , , and in RAW264.7 Macrophages.

In this study, a mixture of , , , and (PPCRE) was investigated for their immuno-enhancing effects, as well as the molecular mechanism of PPCRE in RAW264.7 cells. PPCRE dramatically increased nitric oxide (NO) and prostaglandin E (PGE) generation depending on the concentration while exhibiting no cytotoxicity.