Possible Involvement of Long Non-Coding RNAs and in the Modulation of 5-Fluorouracil Chemosensitivity in Colon Cancer Cells through Increased Extracellular Release of Exosomes.

A growing number of studies have suggested the involvement of long non-coding RNAs as the key players in not just the initiation and progression of the tumor microenvironment, but also in chemotherapy tolerance. In the present study, generated 5-FU-resistant SW480/DR cells were analyzed via cDNA microarray for its aberrant lncRNAs and mRNAs expression in comparison with the 5-FU-susceptible SW480/DS cells. Among the 126 lncRNAs described, lncRNAs , , and have been identified to be significantly upregulated, while lncRNs , , and have been found to be significantly downregulated.

Methicillin-Resistant from Peninsular Malaysian Animal Handlers: Molecular Profile, Antimicrobial Resistance, Immune Evasion Cluster and Genotypic Categorization.

() infections, particularly methicillin-resistant (MRSA) in humans and animals, have become a significant concern globally. The present study aimed to determine the prevalence and antibiogram of isolated from animal handlers in Peninsular Malaysia. Furthermore, the genotypic characteristics of isolates were also investigated.