Complete genome sequence of ST462 harboring the gene on the chromosome, isolated from a pediatric diarrhea patient in Southern Vietnam.

Colistin resistance threatens global health as it compromises the effectiveness of a last-resort antibiotic. We present the complete genome sequence of ST462, which carries the gene, isolated from a pediatric diarrhea case in southern Vietnam. The 5,049,362 bp genome contains 24 resistance genes distributed across 107 contigs.

A New Pathway for the Preparation of Pyrano[2,3-]pyrazoles and molecular Docking as Inhibitors of p38 MAP Kinase.

We report a new pathway to synthesize pyrano[2,3-]pyrazoles and their binding mode to p38 MAP kinase. Pyrano[2,3-]pyrazole derivatives have been prepared through a four-component reaction of benzyl alcohols, ethyl acetoacetate, phenylhydrazine, and malononitrile in the presence of sulfonated amorphous carbon and eosin Y as catalysts. All products were characterized by melting point, H and C NMR, and HRMS (ESI).