Publications by authors named "Mingzi An"
Article Synopsis
- The study aimed to examine the relationship between glycosylated hemoglobin (HbA1c) levels and the occurrence of postherpetic neuralgia (PHN) in patients with herpes zoster (HZ) and type 2 diabetes mellitus (T2DM).
- 90 patients were analyzed, categorized based on their HbA1c levels into good, fair, and poor glycemic control groups, alongside a control group without diabetes.
- Results indicated that patients with higher HbA1c levels had a significantly increased risk of developing PHN post-treatment, suggesting that preoperative HbA1c levels could serve as a predictor for PHN incidence after pulsed radiofrequency treatment in T2DM patients.
Article Synopsis
- Dexmedetomidine, an alpha-2 agonist, may help protect the heart during video-assisted thoracoscopic surgery (VATS) by reducing myocardial injury.
- The study involved patients aged 45 and older, comparing those receiving dexmedetomidine with those given a placebo during general anesthesia.
- Results showed lower levels of high-sensitivity cardiac troponin T (hs-cTnT) in the dexmedetomidine group on both postoperative days 1 and 3, suggesting less heart damage, while the incidence of myocardial injury after surgery was not significantly different between groups.
Purpose: Dexmedetomidine exerts a neuroprotective effect, however, the mechanism underlying this effect remains unclear. This study aimed to explore whether dexmedetomidine can reduce the increase in neurofilament light chain (NfL) protein concentration to play a neuroprotective role during thoracoscopic surgery.
Patients And Methods: Patients aged ≥60 years undergoing general anesthesia for thoracoscopic surgery were randomly assigned to receive dexmedetomidine (group D) or not receive dexmedetomidine (group C).
Background: Minimising postoperative pulmonary complications (PPCs) after thoracic surgery is of utmost importance. A major factor contributing to PPCs is the driving pressure, which is determined by the ratio of tidal volume to lung compliance. Inhalation and intravenous administration of penehyclidine can improve lung compliance during intraoperative mechanical ventilation.
View Article and Find Full Text PDFBackground: In adults undergoing noncardiac surgery, the correlation between intraoperative tidal volume and postoperative acute kidney injury (AKI) is unclear. This study aimed to investigate the effects of low tidal volume ventilation on the incidence of postoperative AKI compared with conventional tidal volume in adults undergoing noncardiac surgery.
Methods: This was a two-center prospective randomized controlled trial on adult patients who underwent noncardiac surgery and had a mechanical ventilation of >60 min.
N6-methyladenosine (m6A) is the most prevalent type of RNA modification. METTL3 in the methyltransferase complex is the core enzyme responsible for methylation. METTL3 selectively catalyzes the adenosines centered in the RRAC motif.
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