Hydrogen sulfide (HS), a gaseous signaling molecule, is involved in a wide range of physiological and pathological processes. HS has been proven to play a beneficial role in lung diseases, and the relationship between perturbations in endogenous HS synthesis and degree with idiopathic pulmonary fibrosis (IPF) has attacted increasing attention. However, the changes in endogenous lung HS levels in the pathological progression of chronic pulmonary diseases remain unclear.
View Article and Find Full Text PDFNanoparticle-based phototherapies, such as photodynamic therapy (PDT) and photothermal therapy (PTT) are effective methods for tumor theranostics. However, there are still some problems such as lack of specificity to the special internal environment and difficulty in tumor localization. In this study, we design a near-infrared (NIR) fluorescent guided tumor therapy nanoplatform Cy-C-S-NPs for tumor therapy and precise localization.
View Article and Find Full Text PDFThe end-Permian mass extinction (EPME) was the most severe extinction event in the past 540 million years, and the Siberian Traps large igneous province (STLIP) is widely hypothesized to have been the primary trigger for the environmental catastrophe. The killing mechanisms depend critically on the nature of volatiles ejected during STLIP eruptions, initiating about 300 kyr before the extinction event, because the atmosphere is the primary interface between magmatism and extinction. Here we report Ni isotopes for Permian-Triassic sedimentary rocks from Arctic Canada.
View Article and Find Full Text PDFThe resonant frequency determined by octagonal split resonant rings (SRRs) is presented and analyzed. The simulated results show that the resonant frequency improves when the opening size of the SRRs becomes larger, and that enhancement of the coupling degree can improve the resonant frequency and widen the band. Four samples are designed to implement the experimental measurement.
View Article and Find Full Text PDFBased on the analysis of rectangular periodic structures, the resonance frequency band is found to be shifted and broadened from low frequency to high frequency by adjustment of the corresponding structure size. Computer simulation shows that a miniature split-ring resonator can enhance and broaden resonance frequency without changing the stop-band location. According to the theoretical parameters, different experimental samples can be fabricated.
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