Analysis and discrimination of adhesive species using ATR-FTIR combined with Raman, and HS-GC-IMS together with multivariate statistical analysis.

Identifying the species and origin of adhesives in criminal investigations aids in narrowing inquiry scope and supporting case detection. This study introduces two advanced combined analytical techniques for distinguishing adhesive species, including attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) combined with Raman spectroscopy, and headspace gas chromatography-ion mobility spectrometry (HS-GC-IMS) together with multivariate statistical analysis. ATR-FTIR categorized seven adhesives into three groups based on the base materials, with further differentiation achieved via Raman spectra.

A multifunctional injectable, self-healing, and adhesive hydrogel-based wound dressing stimulated diabetic wound healing with combined reactive oxygen species scavenging, hyperglycemia reducing, and bacteria-killing abilities.

The proficient handling of diabetic wounds, a rising issue coinciding with the global escalation of diabetes cases, poses significant clinical difficulties. A range of biofunctional dressings have been engineered and produced to expedite the healing process of diabetic wounds. This study proposes a multifunctional hydrogel dressing for diabetic wound healing, which is composed of Polyvinyl Alcohol (PVA) and N-(4-boronobenzyl)-N-(4-boronophenyl)-N, N, N, N-teramethylpropane-1, 3-diaminium (TSPBA), and a dual-drug loaded Gelatin methacryloyl (GM) microgel.

NIR-responsive electrospun nanofiber dressing promotes diabetic-infected wound healing with programmed combined temperature-coordinated photothermal therapy.

Background: Diabetic wounds present significant challenges, specifically in terms of bacterial infection and delayed healing. Therefore, it is crucial to address local bacterial issues and promote accelerated wound healing. In this investigation, we utilized electrospinning to fabricate microgel/nanofiber membranes encapsulating MXene-encapsulated microgels and chitosan/gelatin polymers.

Injectable thermo-responsive Poloxamer hydrogel/methacrylate gelatin microgels stimulates bone regeneration through biomimetic programmed release of SDF-1a and IGF-1.

Injectable hydrogels, offering adaptable drug delivery of growth factors (GFs), hold promise for treating bone defects. To optimize osteogenic efficacy, the release of GFs should mirror the natural bone healing. We developed an injectable thermo-responsive hydrogel/microgels platform for dual GF delivery for bone regeneration.

A Zn-MOF-based mixed matrix membrane as an ultrastable luminescent sensor for selective and visual detection of antibiotics and pesticides in food samples.

The detection of antibiotics and pesticides are of great significance since their residues threaten the health of human beings by accumulation. However, most traditional solid chemical sensors are suffer from the limitations of low sensitivity and economic practicability because of the aggregating nature and unstable of solid sensors. Herein, a new luminescent sensor 1@PMMA (1, [(ZnL)·HO] (HL = 5-(4-(pyridin-4-yl)benzamido)benzene-1,3-dioic acid); PMMA = poly(methyl methacrylate)) was successfully prepared.

NIR-activated electrospun nanodetonator dressing enhances infected diabetic wound healing with combined photothermal and nitric oxide-based gas therapy.

Diabetic wounds pose a challenge to healing due to increased bacterial susceptibility and poor vascularization. Effective healing requires simultaneous bacterial and biofilm elimination and angiogenesis stimulation. In this study, we incorporated polyaniline (PANI) and S-Nitrosoglutathione (GSNO) into a polyvinyl alcohol, chitosan, and hydroxypropyltrimethyl ammonium chloride chitosan (PVA/CS/HTCC) matrix, creating a versatile wound dressing membrane through electrospinning.

Volatile-compound fingerprinting and discrimination of positional isomers in stamp-pad ink tracing using HS-GC-IMS combined with multivariate statistical analysis.

The rising crime rate associated with document forgery has a significant impact on public safety and social stability. In document fraud cases, determining the origin of a particular stamp-pad ink is the most important objective. In this study, a comprehensive analysis of the volatile compounds in quick-drying stamp-pad inks from six commonly used brands were performed for the first time, utilizing a combination of headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) and multivariate statistical analysis methods.

Creation and Evaluation of Human Models with Varied Walking Ability from Motion Capture for Assistive Device Development.

As the world ages, rehabilitation and assistive devices will play a key role in improving mobility. However, designing controllers for these devices presents several challenges, from varying degrees of impairment to unique adaptation strategies of users. To use computer simulation to address these challenges, simulating human motions is required.

Electrospun polyvinyl alcohol-chitosan dressing stimulates infected diabetic wound healing with combined reactive oxygen species scavenging and antibacterial abilities.

Diabetic wounds (DW) are constantly challenged by excessive reactive oxygen species (ROS) accumulation and susceptibility to bacterial contamination. Therefore, the elimination of ROS in the immediate vicinity and the eradication of local bacteria are critical to stimulating the efficient healing of diabetic wounds. In the current study, we encapsulated mupirocin (MP) and cerium oxide nanoparticles (CeNPs) into a polyvinyl alcohol/chitosan (PVA/CS) polymer, and then a PVA/chitosan nanofiber membrane wound dressing was fabricated using electrostatic spinning, which is a simple and efficient method for fabricating membrane materials.

Regulation of Chirality in Metal-Organic Frameworks (MOFs) Based on Achiral Precursors through Substituent Modification.

The generation and regulation of chirality are closely related to the origin of life. Using achiral precursors to spontaneously build chiral MOFs remains a major challenge. Here, a method to synthesize chiral MOFs from achiral precursors by utilizing chiral fragments was achieved.

A stable Cd-MOF as a dual-responsive luminescent biosensor for the determination of urinary diphenyl phosphate and hippuric acid as biomarkers for human triphenyl phosphate and toluene poisoning.

Rapid and accurate determination of biomarkers of human poisoning in real urine is of great significance for the assessment of health status. Herein, a luminescent urea-functionalized metal-organic framework (MOF), {[Cd(L)(bpbix)]·(solv)} (1) (HL = 5,5'-(((naphthalene-1,5-diylbis(azanediyl))bis(carbonyl))bis(azanediyl))diisophthalic acid; bpbix = 4,4'-bis((1-imidazol-1-yl)methyl)biphenyl), has been successfully synthesized, and exhibits good stability in aqueous solutions in the normal urinary pH range and real urine. Complex 1 can serve as a dual-responsive luminescent biosensor for the detection of diphenyl phosphate (DPP) and hippuric acid (HA) as biomarkers of flame retardant triphenyl phosphate and toluene poisoning, and shows the advantages of high sensitivity, rapid response, good anti-interference capability, and reversibility.

Stable Cd Metal-Organic Framework as a Multiresponsive Luminescent Biosensor for Rapid, Accurate, and Recyclable Detection of Hippuric Acid, Nucleoside Phosphates, and Fe in Urine and Serum.

Detecting biomarkers associated with diseases has significant meaning for early prevention, diagnosis, and treatment of diseases. The development of luminescent biosensors for rapid and accurate detection in real urine and serum is urgently desired for human health monitoring. Herein, a luminescent cadmium metal-organic framework, {[Cd(L)(bpbix)]·(solv)} (), was successfully prepared by using a urea-functionalized dicarboxylate ligand, 5-(3-(pyridin-4-yl)ureido)isophthalic acid (HL), 4,4'-bis((1-imidazol-1-yl)methyl)biphenyl (bpbix), and the Cd ion.

Homochiral Eu@MOF Composite for the Enantioselective Detection and Separation of (/)-Ornidazole.

The development of homochiral materials for the enantioselective detection and separation of chiral drugs is in high demand for the pharmaceutical industry. Herein, an anionic homochiral metal-organic framework (HMOF) with generated [MeNH] counterions, {[MeNH][Zn(d-L)(HCO)(OH)]·5HO} (HMOF-), was synthesized using a d-camphorate-derived enantiopure dicarboxylate ligand, 4,4'-[[(1,3)-1,2,2-trimethylcyclopentane-1,3-dicarbonyl]bis(azanediyl)]dibenzoic acid (d-HL) via a simple solvothermal method. Interestingly, HMOF- could be used as a parent framework to encapsulate Eu cations via an ion-exchange process, yielding an Eu@HMOF- composite with dual-luminescent centers.

A Water-Stable Tb-MOF As a Rapid, Accurate, and Highly Sensitive Ratiometric Luminescent Sensor for the Discriminative Sensing of Antibiotics and DO in HO.

The design and development of self-calibrating ratiometric luminescent sensors for the fast, accurate, and sensitive discrimination and determination of pollutants in wastewater is highly desirable for public and environmental health. Herein, a 3D porous Tb(III)-based metal-organic framework (MOF), {[Tb(HL)(HO)]·(solv)} (), was facilely synthesized using a urea-functionalized tetracarboxylate ligand, 5,5'-(((1,4-phenylenebis(azanediyl))bis(carbonyl))bis(azanediyl))diisophthalic acid (HL). The activated framework showed a good water stability in both aqueous solutions at a wide pH range of 2-14 and simulated antibiotic wastewaters.

Molecular engineering in a family of pillared-layered metal-organic frameworks for tuning gas adsorption behavior.

In this work, inspired by a water-assisted three-dimensional supramolecular structure 1, we use a mixed-ligand strategy to form a 3D pillared-layered matrix by the introduction of linear ligands to compete against the water molecules. The resulting analogue microporous MOFs of 2-H, 2-F and 2-N, decorated with different functional groups, similarly show the CO2 uptake. Thanks to the negligible N2 adsorption capacity, enhanced selective adsorption towards CO2 is achieved in compound 2-N.

A water-stable multi-responsive luminescent Zn-MOF sensor for detecting TNP, NZF and CrO in aqueous media.

The wide prevalence of organic and inorganic pollutants in water from various industries is responsible for serious environmental problems and endangers human beings. Therefore, the search for effective methods to detect these pollutants has gained great importance. In this work, a new luminescent MOF, {[Zn(L)(bpe)]·DMF} (1) [HL = 4,4'-((naphthalene-1,4-dicarbonyl)bis(azanediyl))dibenzoic acid, bpe = 1,2-bis(4-pyridyl)ethene], was solvothermally synthesized and structurally characterized.

A water-stable homochiral luminescent MOF constructed from an achiral acylamide-containing dicarboxylate ligand for enantioselective sensing of penicillamine.

A water-stable homochiral luminescent metal-organic framework (HLMOF), {[Cd(l)(4,4'-bipy)]·DMA·5H2O}n (1), was obtained by a spontaneous symmetry-breaking crystallization from achiral precursors without any enantiopure auxiliary. The homochirality of 1 was confirmed by single-crystal X-ray diffraction and CD spectroscopy. Complex 1 exhibits an interesting enantioselective sensing of d/l-penicillamine in water.

A Water-Stable 3D Luminescent Metal-Organic Framework Based on Heterometallic [EuZn] Clusters Showing Highly Sensitive, Selective, and Reversible Detection of Ronidazole.

A water-stable 3D luminescent metal-organic framework (MOF), [EuZn(μ-OH)(NDC)(HO)] (1), constructed from heterometallic [EuZn] clusters and electron-rich π-conjugated 1,4-naphthalenedicarboxylic acid (HNDC) ligands exhibits highly sensitive, selective, and reversible detection of ronidazole, which represents the first example of luminescent MOFs based on Ln-TM heterometallic clusters for the detection of antibiotics in aqueous solution.

A two-dimensional cadmium(II) coordination polymer based on 5-(pyridin-4-yl)isophthalic acid: poly[[tetraaquabis[μ₃-5-(pyridin-4-yl)isophthalato]dicadmium(II)] pentahydrate].

The title Cd(II) compound, {[Cd2(C13H7NO4)2(H2O)4]·5H2O}n, was synthesized by the hydrothermal reaction of Cd(NO3)2·4H2O and 5-(pyridin-4-yl)isophthalic acid (H2L). The asymmetric unit contains two crystallographically independent Cd(II) cations, two deprotonated L(2-) ligands, four coordinated water molecules and five isolated water molecules. One of the Cd(II) cations adopts a six-coordinate octahedral coordination geometry involving three O atoms from one bidentate chelating and one monodentate carboxylate group of two different L(2-) ligands, one N atom of another L(2-) ligand and two coordinated water molecules.