Publications by authors named "Mingyu Zhang"

Digital technology interventions (DTIs) are seen as promising interventions to prevent or delay cognitive decline in older adults, yet evidence from reviews is not conclusive. The aim of this study is to explore the effectiveness of DTIs in improving older adults' cognitive function while taking study design and intervention characteristics as moderators. We searched the PubMed, Embase, CINAHL, PsycINFO, and Scopus databases up to May 26, 2023.

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Van Hove singularity (vHs), the singularity point of density of states (DOS) in crystalline solids, is a research hotspot in emerging phenomena such as light-matter interaction, superconducting, and quantum anomalous Hall effect. Although the significance of vHs in photothermoelectric (PTE) effect has been recognized, its integral role in electron excitation and thermoelectric effect is still unclear, particularly in the mid-infrared band that suffers from Pauli blockade in semimetals. Here, we unveil the Fermi-level-modulated PTE behavior in the vicinity of vHs in carbon nanotubes, employing ionic-liquid gating.

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Developing ultraviolet (UV), visible (Vis) and near-infrared (NIR) responsive photocatalysts for Cr(VI) reduction is valuable. Herein, a 0-dimensional/1-dimensional (0D/1D) S-scheme AgS/BiSI hetero-structured photocatalyst was successfully synthesized, which displays greatly enhanced Cr(VI) removal activity either under UV, Vis or NIR light irradiation. In-situ characterization technique and theoretical calculation confirm that an internal electric field (IEF), directing from AgS to BiSI, exists between the interface, which facilitates the spatial-oriented separation of photoirradiated carriers.

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The safety of nuclear energy, as a low-carbon energy source, has received widespread attention. One of the concerns is the appropriate handling of volatile radioactive elements (e.g.

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Background: Orthostatic hypertension is an emerging risk factor for adverse events. Recent consensus statements combine an increase in blood pressure upon standing with standing hypertension, but whether these 2 components have similar risk associations with cardiovascular disease (CVD) is unknown.

Methods: The ARIC study (Atherosclerosis Risk in Communities) measured supine and standing blood pressure during visit 1 (1987-1989).

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Investigate the impact of diaphragm sellae competence on surgical outcomes and risk factors for postoperative hypothalamic injury (HI) in patients undergoing endoscopic transsphenoidal surgery (ETS) for infradiaphragmatic craniopharyngiomas (ICs). A retrospective analysis of 54 consecutive patients (2016-2023) with ICs treated by ETS was conducted. All tumors originated from the sellar region inferior to the diaphragm sellae and were classified into two subtypes in terms of diaphragm sellae competence: IC with competent diaphragm sellae (IC-CDS) and IC with incompetent diaphragm sellae (IC-IDS).

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Polycentric urban development is promoted by urban planners and policy makers for its perceived benefits of alleviating urban issues. Theoretically, a polycentric urban structure is formed when different demographic groups present a collection of diverse and unique housing location preferences. Yet, only limited empirical studies have fully captured the complex effects of demographic characteristics on urban polycentric structures.

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Background: Prenatal per- and polyfluoroalkyl substance (PFAS) exposures are associated with adverse offspring health outcomes, yet the underlying pathological mechanisms are unclear. Cord blood metabolomics can identify potentially important pathways associated with prenatal PFAS exposures, providing mechanistic insights that may help explain PFAS' long-term health effects.

Methods: The study included 590 mother-infant dyads from the Boston Birth Cohort.

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Fluctuations of intracellular HO level are intricately linked to diverse biological processes, e.g., cellular proliferation, biosynthesis, and metabolic activities.

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Article Synopsis
  • * It reviews advancements in the activation of C-O bonds in aryl, vinyl, and benzylic ethers, focusing on various catalytic systems like transition metal and photoredox catalysis.
  • * The newly developed methods allow for C-O bond activation under mild conditions, which could enhance the late-stage functionalization of pharmaceuticals, while also addressing current limitations and future directions in the field.
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The co-loading of radionuclides and small-molecule chemotherapeutic drugs as nanotheranostic platforms using nanozymes holds tremendous potential for imaging-guided synergistic therapy. This study presents such nanotheranostic platform (Lu-MFeCu@Tan) via co-assembling Lu radionuclide and tanshinone (Tan) into Fe/Cu dual-metal nanozyme (MFeCu). This platform simultaneously enables single-photon emission computed tomography (SPECT) imaging and a quadruple-synergistic tumor therapy approach, including internal radioisotope therapy (RIT), catalysis therapy, chemotherapy, and MFeCu-mediated ferroptosis and cuproptosis therapy.

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We report an efficient total synthesis of (±)-phaeocaulisin A, a guaianolide sesquiterpene natural product possessing a complex tetracyclic skeleton embedded with an oxaspirolactone and a fused bicyclic lactone, four oxygen-containing stereocenters, and an 8-oxabicyclo[3.2.1]octane core.

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Multiple researchers have effectively utilized InSAR for early identification research in southwest China. However, the intricate geological structure in this region includes deeply buried and unpredictable anti-dip stratiform rock slopes, posing an additional challenge for InSAR remote sensing. This study establishes a coupling relationship between slope topple deformation patterns and surface macro-deformation characteristics through a centrifuge model test, analyzing slope bending and topple deformation stages.

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Background: In recent decades, depressive symptoms have intensified among Chinese adolescents, particularly those from single-parent homes, who are presumed to face heightened mental health risks. Nonetheless, economic growth, fertility policy reforms, and cultural openness have enhanced the adaptability of these adolescents, enabling them to better manage depressive symptom risks.

Aim And Method: This study aims to scrutinize the evolving trends of depressive symptoms and explore the related social factors among Chinese adolescents from single-parent families.

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Article Synopsis
  • * The protein nucleophosmin 1 (NPM1) has been found to increase in CKD patients, impacting kidney cell function and contributing to the fibrogenesis process.
  • * Lowering NPM1 levels boosts ferroptosis activity and reduces renal fibrosis, while using a ferroptosis inhibitor (Fer-1) also decreases NPM1 expression and helps alleviate kidney damage.
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  • * A new method using stereoselective asymmetric reactions combined with tandem ion mobility-mass spectrometry (IM-MS) has been developed for better detection and analysis of these C═C bonds.
  • * This innovative approach enabled the study of lipid changes in bacterial membranes under stress and the distribution of unsaturated lipids in rats post-injury, showcasing IM-MS's potential for various molecular applications.
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  • CO is a major pollutant in biogas, reducing its energy content, and membrane separation technology is a promising method for large-scale biogas purification.
  • The study focuses on creating bilayer hybrid composite membranes by combining packed molecular sieves (TS-1 or ZSM-5) with cellulose derivatives on PVDF substrates.
  • The most effective membrane, PVDF/EC-ZSM-5, demonstrated impressive CO permeability and selectivity, suggesting it could be an efficient solution for CO separation in industrial biogas purification processes.
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Microcolumn gel immunoassay (MGIA) has the ability to meet the requirements of clinical diagnosis due to its reliable sensitivity and accuracy. However, traditional MGIA exhibits limitations including inadequate portability, low throughput, and extended analysis time. To address these challenges, we combined MGIA with microfluidic technology, demonstrating a centrifugal microfluidic-based microcolumn gel immunoassay (μMGIA) platform for blood typing of clinical samples.

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Diffuse gliomas in adults are highly infiltrative and largely incurable. Whole exome sequencing (WES) has been demonstrated very useful in genetic analysis. Here WES was performed to characterize genomic landscape of adult-type diffuse gliomas to discover the diagnostic, therapeutic and prognostic biomarkers.

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