Are different TOD circles oriented towards sustainability amidst urban shrinkage? Evidence from urban areas to suburbs in the Tokyo metropolitan area.

Transit-Oriented Development (TOD) is a prominent urban development approach aimed at maximizing the number of residential, commercial, and walkable spaces within the catchment area of public transportation. Despite its widespread discussion, the definition of the TOD catchment area remains ambiguous. This study expands the research scope of TOD catchment areas by introducing the concept of three TOD circles and examines their relevance within the context of urban shrinkage in the Tokyo Metropolitan Area over time.

Incorporation of Graphene Oxide Quantum Dots in Gradient Layers of Polyethersulphone Nanofiltration Membranes for Nitrate Rejection from Aqueous Solution.

Graphene oxide quantum dots (GOQDs) have been widely used to prepare nanofiltration membranes due to the merits of excellent dispersity, ultrasmall size, and unique properties related to graphene. In this study, we first prepared the polyethersulphone-based nanofiltration (PES-NF) membrane via an interfacial polymerization process using a piperazine and -phenylenediamine mixed solution as the aqueous phase. Then GOQDs were incorporated into the top-down gradient structured layers (i.

Effects of short-term preoperative intranasal dexmedetomidine plus conventional treatment on delirium following cardiac surgery in patients with sleep disorders.

Study Objectives: To assess whether preoperative dexmedetomidine (DEX) nasal drips combined with conventional treatment could mitigate the occurrence of postoperative delirium (POD).

Design: A prospective randomised controlled study.

Setting: The cardiac surgery intensive care unit (CSICU) and patient hospitalisation ward at a university hospital.

Effects of dexmedetomidine dosage on the short-term cognitive function of elderly patients undergoing cardiac surgery.

Background: This study aimed to investigate the effects of perioperative dexmedetomidine (DEX) infusion rates on the postoperative short-term cognitive function.

Methods: A total of 88 patients aged ≥ 60 years who underwent cardiac surgery from January 2022 to November 2022 at the First Affiliated Hospital of The University of Science and Technology of China (USTC) were included. Based on a single-center pilot analysis, patients were divided into two groups according to the rate of intraoperative DEX infusion, which started after tracheal intubation and continued until 1 h before extubation in the cardiac surgery intensive care unit.

Effect of Transcutaneous Electrical Acupoint Stimulation Combined with Transversus Abdominis Plane Block on Postoperative Recovery in Elderly Patients Undergoing Laparoscopic Gastric Cancer Surgery: A Randomized Controlled Trial.

Introduction: This study assessed the influence of transcutaneous electrical acupoint stimulation (TEAS) combined with transversus abdominis plane block (TAPB) on the recovery of elderly patients undergoing laparoscopic gastric cancer surgery.

Methods: Ninety patients (age ≥ 60 years) undergoing laparoscopic gastric cancer surgery were randomly divided into general anesthesia group (group G), TAPB group (group NG), and TEAS combined with TAPB group (group NTG). Patients in the NTG group received TEAS at PC6, LI4, and ST36 acupoints and TAPB.

Efficacy and Complications of Unilateral Biportal Endoscopic Spinal Surgery for Lumbar Spinal Stenosis: A Meta-Analysis and Systematic Review.

Objective: As an emerging minimally invasive endoscopic technique, unilateral biportal endoscopic spinal surgery (UBESS) has the advantages of flexibility, a wide and clear field of view, and less soft tissue damage. However, the clinical evidence is insufficient and controversy exists regarding UBESS for the treatment of lumbar spinal stenosis (LSS). In the present meta-analysis, we investigated the clinical efficacy and complications of UBESS for the treatment of LSS.

Dexmedetomidine Protects Human Renal Tubular Epithelial HK-2 Cells against Hypoxia/Reoxygenation Injury by Inactivating Endoplasmic Reticulum Stress Pathway.

Objective: The study was aimed to investigate the effects and potential mechanisms of Dexmedetomidine (Dex) on hypoxia/reoxygenation (H/R) injury in human renal tubular epithelial HK-2 cells.

Materials And Methods: In this experimental study, HK-2 cells were divided into four groups: control group, Dex group, H/R group, and Dex+H/R group. The cells in control group received no treatment, and cells in Dex group were only treated with 0.

A comparative study of serotonin and norepinephrine as adjuncts to improve cutaneous antinociception of mexiletine in response to skin pinpricks in rats.

As adrenaline, serotonin and norepinephrine are two other vasoconstrictors and both of which have been proved to increase the quality and duration of local anesthetics when added as adjuvants. However, the difference in the improvement of the nociception of local anesthetics between the two adjuvants remains unclear. The purpose of this study was to assess the cutaneous nociception of mexiletine by coadministration with serotonin and norepinephrine.

Comparison of Adrenaline and Dexmedetomidine in Improving the Cutaneous Analgesia of Mexiletine in Response to Skin Pinpricks in Rats.

Background: Adrenaline (Adr) and dexmedetomidine (Dex) are commonly used adjuvants of local anesthetics; however, the difference in the improvement of analgesia of local anesthetics between the 2 adjuvants remains unclear.

Objective: The objective of this experimental research was to evaluate the cutaneous analgesic effect of mexiletine (Mex) by coadministration with Dex or Adr.

Methods: The effect of a nociceptive block was assessed based on the inhibition of the cutaneous trunci muscle reflex in response to skin pinpricks in rats.

The effect of dexmedetomidine on renal function in patients undergoing cardiac valve replacement under cardiopulmonary bypass: A double-blind randomized controlled trial.

Study Objective: We attempted to explore the effect of Dex on renal function in patients with cardiac valve replacement under cardiopulmonary bypass (CPB).

Design: We designed a prospective, randomized, placebo-controlled, single-center, parallel-arm double-blind trial.

Setting: Operating room.

The efficacy of pedicle screw instrument in treatment of irreducible atlantoaxial dislocation.

Objective: To explore the effect of pedicle screw instrument in treatment of irreducible atlantoaxial dislocation.

Patients And Method: From June 2003 to February 2009, 14 cases of atlas dislocation with upper cervical cord compression were enrolled and anterior transoral soft tissue release combined with posterior reduction and pedicle screw fixation were performed. CT, MRI and radiograph were used preoperatively, and screw placement and bone graft were administered in all cases intraoperatively.