Identification of prognostic stemness-related genes in kidney renal papillary cell carcinoma.

Background: Kidney renal papillary cell carcinoma (KIRP) is the second most prevalent malignant cancer originating from the renal epithelium. Nowadays, cancer stem cells and stemness-related genes (SRGs) are revealed to play important roles in the carcinogenesis and metastasis of various tumors. Consequently, we aim to investigate the underlying mechanisms of SRGs in KIRP.

A gene signature linked to fibroblast differentiation for prognostic prediction of mesothelioma.

Background: Malignant mesothelioma is a type of infrequent tumor that is substantially related to asbestos exposure and has a terrible prognosis. We tried to produce a fibroblast differentiation-related gene set for creating a novel classification and prognostic prediction model of MESO.

Method: Three databases, including NCBI-GEO, TCGA, and MET-500, separately provide single-cell RNA sequencing data, bulk RNA sequencing profiles of MESO, and RNA sequencing information on bone metastatic tumors.

Tele-Instruction Tool for Multiple Lay Responders Providing Cardiopulmonary Resuscitation in Telehealth Emergency Dispatch Services: Mixed Methods Study.

Background: Telephone-assisted cardiopulmonary resuscitation (T-CPR) has proven to be a crucial intervention in enhancing the ability of lay responders to perform cardiopulmonary resuscitation (CPR) during telehealth emergency services. While the majority of established T-CPR protocols primarily focus on guiding individual rescuers, there is a lack of emphasis on instructing and coordinating multiple lay responders to perform resuscitation collaboratively.

Objective: This study aimed to develop an innovative team-based tele-instruction tool to efficiently organize and instruct multiple lay responders on the CPR process and to evaluate the effectiveness and feasibility of the tool.

Porous spherical calcium aluminate-supported CaO-based pellets manufactured via biomass-templated extrusion-spheronization technique for cyclic CO capture.

Calcium looping has been proposed as one of the most promising technologies for CO capture to mitigate the growing problem of global warming. However, the loss in capacity and attrition are two issues lying on the way to practical application for calcium looping process. To improve CO capture performance and mechanical strength of CaO sorbents, a biomass templated extrusion-spheronization palletization technique was employed to manufacture porous calcium aluminate-supported CaO-based pellets.