Preparation of 6-Amino-N-hydroxyhexanamide-Modified Porous Chelating Resin for Adsorption of Heavy Metal Ions.

The pollution of water bodies by heavy metal ions has recently become a global concern. In this experiment, a novel chelating resin, D851-6-AHHA, was synthesized by grafting 6-amino-N-hydroxyhexanamide (6-AHHA) onto the (-CHN-(CHCOOH)) group of the D851 resin, which contained a hydroxamic acid group, amide group, and some carboxyl groups. This resin was developed for the purpose of removing heavy metal ions, such as Cr(III) and Pb(II), from water.

An ultra-sensitive biosensor based on surface plasmon resonance and weak value amplification.

An ultra-sensitive phase plasmonic sensor combined with weak value amplification is proposed for the detection of IgG, as a model analyte. Phase detection is accomplished by self-interference between the p-polarization and the s-polarization of the light. With the principles of weak value amplification, a phase compensator is used to modulate the coupling strength and enhance the refractive index sensitivity of the system.

Targeting and cytotoxicity of chimeric antigen receptor T cells grafted with PD1 extramembrane domain.

Background: Immunosuppression induced by programmed cell death protein 1 (PD1) presents a significant constraint on the effectiveness of chimeric antigen receptor (CAR)-T therapy. The potential of combining PD1/PDL1 (Programmed cell death 1 ligand 1) axis blockade with CAR-T cell therapy is promising. However, developing a highly efficient and minimally toxic approach requires further exploration.

Analysis of Microbial Diversity and Metabolites in Sauerkraut Products with and without Microorganism Addition.

The microbial compositions and metabolites of fermented sauerkraut with and without the addition of microorganisms have been compared. The OTU clustering, nonvolatile compounds, volatile compounds and associations between bacterial taxa and metabolites were analyzed by 16S rRNA high-throughput sequencing technology, ultra performance liquid chromatography (UPLC), gas chromatography ion mobility mass spectrometry (GC-IMS) and the O2PLS model studies. The results showed that at the phylum level, the microbial species in the four sauerkraut types consisted mainly of the phyla and , but different modes of microbial addition formed their own unique microbial communities.

Reducing Hinge Flexibility of CAR-T Cells Prolongs Survival With Low Cytokines Release.

Chimeric antigen receptor (CAR)-modified T cells targeting CD19 demonstrate unparalleled responses in B cell malignancies. However, high tumor burden limits clinical efficacy and increases the risk of cytokine release syndrome and neurotoxicity, which is associated with over-activation of the CAR-T cells. The hinge domain plays an important role in the function of CAR-T cells.

What Affects Older Adults' Viewing Behaviors in Neighborhood Open Space: A Study in Hong Kong.

Research on older adults' behaviors, living environments, and their quality of life (QoL) has grown rapidly. Viewing behaviors, although broadly acknowledged as critical for older adults' QoL, have not been systematically examined in situ. What affects the viewing behaviors of older adults in neighborhood open space (NOS) is still unclear.

Vitamin D deficiency relation to sepsis, paediatric risk of mortality III score, need for ventilation support, length of hospital stay, and duration of mechanical ventilation in critically ill children: A meta-analysis.

Introduction: Vitamin D deficiency in children is related to the augmented risk of bone illnesses, but its effect on critically ill children is still conflicting. This meta-analysis study was performed to assess the relationship between vitamin D deficiency in children and sepsis, paediatric risk of mortality III score, need for ventilation support, length of hospital stay, and duration of mechanical ventilation in critically ill children.

Methods: Through a systematic literature search up to June 2020, 16 studies with 2382 children, 1229 children of them with vitamin D deficiency, were found recording relationships between vitamin D deficiency and sepsis, paediatric risk of mortality III score, need for ventilation support, length of hospital stay, and/or duration of mechanical ventilation.

miRNA-10a-5p Alleviates Insulin Resistance and Maintains Diurnal Patterns of Triglycerides and Gut Microbiota in High-Fat Diet-Fed Mice.

miRNA-10a is rhythmically expressed and regulates genes involved in lipid and glucose metabolism. However, the effects of miRNA-10a on obesity and glucose intolerance, as well as on the diurnal pattern of expression of circadian clock genes, remain unknown. We explored the effects of miRNA-10a-5p on insulin resistance and on the diurnal patterns of serum triglycerides and gut microbiota in high-fat diet- (HFD-) fed mice.

A Generalized Chirp-Scaling Algorithm for Geosynchronous Orbit SAR Staring Observations.

Geosynchronous Orbit Synthetic Aperture Radar (GEO SAR) has recently received increasing attention due to its ability of performing staring observations of ground targets. However, GEO SAR staring observation has an ultra-long integration time that conventional frequency domain algorithms cannot handle because of the inaccurately assumed slant range model and existing azimuth aliasing. To overcome this problem, this paper proposes an improved chirp-scaling algorithm that uses a fifth-order slant range model where considering the impact of the "stop and go" assumption to overcome the inaccuracy of the conventional slant model and a two-step processing method to remove azimuth aliasing.

Projective multiview structure and motion from element-wise factorization.

The Sturm-Triggs type iteration is a classic approach for solving the projective structure-from-motion (SfM) factorization problem, which iteratively solves the projective depths, scene structure, and camera motions in an alternated fashion. Like many other iterative algorithms, the Sturm-Triggs iteration suffers from common drawbacks, such as requiring a good initialization, the iteration may not converge or may only converge to a local minimum, and so on. In this paper, we formulate the projective SfM problem as a novel and original element-wise factorization (i.